Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 10/20 | 0.61 |
| ▸ | ESR2 | Q92731 | 9/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TYR | P14679 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | HTR6 | P50406 | 1/20 | 0.46 |
| ▸ | ESRRG | P62508 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SHBG | P04278 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3400019 | 0.83 | ESR1 (0.48) | ESR1ESR2CYP3A4ALDH1A1TSHR | |
| SCHEMBL3024282 | 0.82 | ESR1 (0.63) | ESR1ESR2CYP3A4ALDH1A1TSHR | |
| SCHEMBL9567886 | 0.82 | ESR1 (0.63) | ESR1ESR2CYP3A4ALDH1A1TSHR | |
| SCHEMBL27918575 | 0.79 | ESR1 (0.48) | ESR1ESR2CYP3A4ALDH1A1TSHR | |
| SCHEMBL9682941 | 0.78 | ESR1 (0.59) | ESR1ESR2CYP3A4ALDH1A1TSHR | |
| SCHEMBL7916602 | 0.78 | ESR1 (0.59) | ESR1ESR2CYP3A4ALDH1A1TSHR | |
| SCHEMBL9243349 | 0.78 | ESR1 (0.70) | ESR1ESR2CYP3A4ALDH1A1TSHR | |
| SCHEMBL11481836 | 0.78 | ESR1 (0.53) | ESR1ESR2CYP3A4ALDH1A1TSHR | |
| SCHEMBL8784146 | 0.78 | TSHR (0.50) | ESR1ESR2CYP3A4ALDH1A1TSHR | |
| SCHEMBL9567870 | 0.78 | ESR1 (0.63) | ESR1ESR2CYP3A4ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6217995-B1 | TRANSPARENT POLYCARBONATE OR POLYESTERCARABONATE CONTAINING CYCLIC ALIPHATIC GROUP, HAVING A VISIBLE LIGHT TRANSMITTANCE MORE THAN 80% AND A GLASS TRANSITION TEMPERATURE LESS THAN 80 DEGREE C. EXHIBIT BIREFRINGENCE INDEX LESS THAN 15 NM | MITSUBISHI CHEMICAL CORPORATION (JP) | 2001-04-17 | — | — | US | disclosed |
| US-5777009-A | Flame retardant low Tg polyestercarbonate | GENERAL ELECTRIC COMPANY (US) | 1998-07-07 | — | — | US | disclosed |
| EP-0838503-A1 | Flame retardant composition of polyerstercarbonate, halogenated polycarbonate, potassium diphenylsulfone sulfonate and polytetrafluoroethylene | GENERAL ELECTRIC COMPANY (US) | 1998-04-29 | — | — | EP | disclosed |
| EP-0563316-B1 | POLYOXAZOLIDONES | FULLER H B LICENSING FINANC (US) | 1995-03-08 | — | — | EP | disclosed |
| EP-0563316-A1 | POLYOXAZOLIDONES. | FULLER H B LICENSING FINANC (US) | 1993-10-06 | — | — | EP | disclosed |
| US-5138016-A | Using zinc halide catalyst | H. B. FULLER COMPANY (US) | 1992-08-11 | — | — | US | disclosed |
| WO-1992011304-A1 | NOVEL CATALYST FOR PRODUCTION OF OXAZOLIDINE COMPOUNDS | H.B. FULLER LICENSING & FINANCING INC. (US) | 1992-07-09 | — | — | WO | disclosed |
| US-4766158-A | CATALYTIC REACTION OF POLYISOCYANATES AND POLYEPOXIDE | OLIN CORPORATION (US) | 1988-08-23 | — | — | US | disclosed |
| US-4699931-A | REACTING POLYISOCYANATE WITH POLYEPOXIDE-THERMAL STABILITY | OLIN CORPORATION (US) | 1987-10-13 | — | — | US | disclosed |
| US-4412012-A | CURING AGENT IS KETONE BLOCKED PRIMARY AMINE | ALBANY INTERNATIONAL CORP. (US) | 1983-10-25 | — | — | US | disclosed |
| US-4410639-A | KETONE BLOCKED PRIMARY AMINE CURING AGENT | ALBANY INTERNATIONAL CORP. (US) | 1983-10-18 | — | — | US | disclosed |
| US-4066628-A | REACTING ORGANIC ISOCYANATE WITH AN EPOXIDE | MITSUBISHI CHEMICAL INDUSTRIES LTD. (JA) | 1978-01-03 | — | — | US | disclosed |