Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 12/20 | 0.59 |
| ▸ | ESR2 | Q92731 | 11/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TYR | P14679 | 1/20 | 0.45 |
| ▸ | AR | P10275 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | HTR6 | P50406 | 1/20 | 0.45 |
| ▸ | ESRRG | P62508 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SHBG | P04278 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9567886 | 0.80 | ESR1 (0.63) | ESR1ESR2CYP3A4ALDH1A1TSHR | |
| SCHEMBL3024282 | 0.80 | ESR1 (0.63) | ESR1ESR2CYP3A4ALDH1A1TSHR | |
| SCHEMBL7916588 | 0.78 | ESR1 (0.61) | ESR1ESR2CYP3A4ALDH1A1TSHR | |
| SCHEMBL7916602 | 0.77 | ESR1 (0.59) | ESR1ESR2CYP3A4ALDH1A1TSHR | |
| SCHEMBL9243349 | 0.77 | ESR1 (0.70) | ESR1ESR2CYP3A4ALDH1A1TSHR | |
| SCHEMBL10865394 | 0.77 | ESR1 (0.46) | ESR1ESR2CYP3A4ALDH1A1TSHR | |
| SCHEMBL9567870 | 0.76 | ESR1 (0.63) | ESR1ESR2CYP3A4ALDH1A1TSHR | |
| SCHEMBL8614758 | 0.76 | ESR1 (0.57) | ESR1ESR2CYP3A4ALDH1A1TSHR | |
| SCHEMBL5375638 | 0.76 | ESR1 (0.57) | ESR1ESR2CYP3A4ALDH1A1TSHR | |
| SCHEMBL27277 | 0.74 | ESR1 (1.00) | ESR1ESR2CYP3A4ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3243876-A1 | POLYCARBONATE RESIN COMPOSITION FOR THIN OPTICAL COMPONENTS, AND THIN OPTICAL COMPONENT | Mitsubishi Engineering-Plastics Corporation (JP) | 2017-11-15 | — | — | EP | disclosed |
| EP-0469492-A2 | Polymer modified adducts of epoxy resins and active hydrogen containing compounds containing mesogenic moieties | THE DOW CHEMICAL COMPANY (US) | 1992-02-05 | — | — | EP | disclosed |
| EP-0299086-A1 | DAMPING MATERIAL COMPOSITIONS AND DAMPING MATERIALS | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1989-01-18 | — | — | EP | disclosed |