Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7912940 | 0.86 | ACHE (0.53) | ACHEKDM4EALDH1A1NPC1OPRK1 | |
| SCHEMBL7911353 | 0.80 | KDM4E (0.52) | ACHEKDM4EALDH1A1NPC1OPRK1 | |
| SCHEMBL7913223 | 0.80 | ACHE (0.44) | ACHEKDM4EALDH1A1NPC1OPRK1 | |
| SCHEMBL7913070 | 0.79 | KDM4E (0.75) | ACHEKDM4EALDH1A1NPC1GAA | |
| SCHEMBL7903030 | 0.78 | KDM4E (0.73) | ACHEKDM4EALDH1A1NPC1GAA | |
| SCHEMBL7902779 | 0.78 | KDM4E (0.73) | ACHEKDM4EALDH1A1NPC1GAA | |
| SCHEMBL7913313 | 0.76 | KDM4E (0.50) | ACHEKDM4EALDH1A1NPC1OPRK1 | |
| SCHEMBL7910373 | 0.75 | ACHE (0.56) | ACHEKDM4EALDH1A1NPC1GAA | |
| SCHEMBL927447 | 0.75 | SLC9A1 (0.39) | ACHEKDM4EALDH1A1NPC1KMT2A | |
| Dimethylamine SCHEMBL7910311 | 0.74 | KDM4E (0.68) | ACHEKDM4EALDH1A1NPC1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6258829-B1 | ANTIARRTHMIA AGENTS AND CARDIOVASCULAR DISORDERS | TOA EIYO LTD. (JP) | 2001-07-10 | — | — | US | disclosed |
| EP-0972767-A1 | CYCLOALKA[b]PYRIDINE-3-CARBONYLGUANIDINE DERIVATIVES, PROCESS FOR PRODUCING THE SAME, AND DRUGS CONTAINING THE SAME | TOA EIYO LTD. (JP) | 2000-01-19 | — | — | EP | disclosed |