Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VNN1 | O95497 | 6/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL926592 | 0.83 | NPC1 (0.37) | ALDH1A1NPC1MAPT | |
| SCHEMBL927202 | 0.80 | NPC1 (0.35) | ALDH1A1NPC1MAPT | |
| SCHEMBL7916701 | 0.78 | NPC1 (0.39) | ALDH1A1NPC1MAPTLMNASMN1; SMN2 | |
| SCHEMBL7913178 | 0.77 | NPC1 (0.38) | ALDH1A1NPC1MAPTSMN1; SMN2 | |
| SCHEMBL927099 | 0.75 | NPC1 (0.32) | ALDH1A1NPC1MAPT | |
| SCHEMBL7916777 | 0.75 | ALDH1A1 (0.37) | ALDH1A1NPC1MAPT | |
| SCHEMBL7902769 | 0.75 | ALDH1A1 (0.37) | ALDH1A1NPC1MAPTLMNASMN1; SMN2 | |
| SCHEMBL8132944 | 0.74 | MAPT (0.36) | ALDH1A1NPC1MAPTSMN1; SMN2 | |
| SCHEMBL7916790 | 0.74 | CHRNB2 (0.35) | ALDH1A1PDE4DCHRNB2CHRNA7CHRNA4 | |
| SCHEMBL7916783 | 0.73 | ALDH1A1 (0.45) | ALDH1A1MAPTPDE4DBRD4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6258829-B1 | ANTIARRTHMIA AGENTS AND CARDIOVASCULAR DISORDERS | TOA EIYO LTD. (JP) | 2001-07-10 | — | — | US | disclosed |
| EP-0972767-A1 | CYCLOALKA[b]PYRIDINE-3-CARBONYLGUANIDINE DERIVATIVES, PROCESS FOR PRODUCING THE SAME, AND DRUGS CONTAINING THE SAME | TOA EIYO LTD. (JP) | 2000-01-19 | — | — | EP | disclosed |