Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 4/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | AGXT | P21549 | 2/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5211821 | 0.85 | NOS1 (0.49) | CYP3A4KDM4EMAPTBCHECHRM2 | |
| SCHEMBL11623741 | 0.83 | CYP3A4 (0.55) | CYP3A4CYP1A2PKMALOX15NFKB1 | |
| SCHEMBL7917100 | 0.82 | CHRM2 (0.60) | CYP3A4CYP1A2PKMALOX15NFKB1 | |
| SCHEMBL6489910 | 0.81 | MAOB (0.54) | IDO1AGXTTAAR1FFAR1FYN | |
| Hydrochloric Acid SCHEMBL23924018 | 0.81 | IDO1 (0.61) | CYP3A4CYP1A2PKMALOX15NFKB1 | |
| SCHEMBL14117318 | 0.79 | KDM4E (0.56) | MAPK1KDM4EBCHEIDO1ALDH1A1 | |
| SCHEMBL21116575 | 0.79 | IDO1 (0.50) | KDM4EBCHEIDO1ALDH1A1AGXT | |
| SCHEMBL11617606 | 0.79 | TSHR (0.51) | KDM4EKMT2AALDH1A1 | |
| SCHEMBL18259471 | 0.78 | BCHE (0.73) | PKMMAPK1KDM4EMAPTKMT2A | |
| SCHEMBL30177533 | 0.78 | TAAR1 (0.69) | KDM4ECHRM2TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6291485-B1 | TREATMENT OF POST-PTCA RESTENOSIS | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 2001-09-18 | — | — | US | disclosed |
| EP-1002797-A1 | 4,5-DIHYDRO- 1H]-BENZ g]INDAZOLE-3-CARBOXYLIC ACID DERIVATIVES | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 2000-05-24 | — | — | EP | disclosed |