Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.80 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.74 |
| ▸ | MEN1 | O00255 | 2/20 | 0.74 |
| ▸ | NPC1 | O15118 | 1/20 | 0.74 |
| ▸ | RAB9A | P51151 | 1/20 | 0.74 |
| ▸ | POLB | P06746 | 2/20 | 0.70 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.67 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1796007 | 0.90 | TAAR1 (0.69) | TAAR1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL6377511 | 0.85 | MTNR1A (0.68) | TAAR1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL17117231 | 0.84 | HPGD (0.73) | TAAR1MTNR1AMTNR1BHPGD | |
| SCHEMBL14241869 | 0.84 | MTNR1A (0.72) | TAAR1MTNR1AMTNR1BHPGD | |
| SCHEMBL11896371 | 0.83 | MTNR1A (0.77) | TAAR1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL28465013 | 0.81 | NPC1 (0.81) | TAAR1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL6380843 | 0.81 | ALDH1A1 (0.70) | TAAR1KMT2AMEN1POLBALDH1A1 | |
| SCHEMBL28000837 | 0.81 | KMT2A (0.64) | TAAR1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL1010724 | 0.80 | MTNR1A (1.00) | TAAR1MTNR1AMTNR1BHPGD | |
| SCHEMBL14893135 | 0.79 | MTNR1A (0.74) | TAAR1KMT2AMEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6225352-B1 | USEFUL AS AGENTS IN THE TREATMENT OF CANCER, ALZHEIMERS DISEASE, THROMBOSIS, INFLAMMATORY DISEASES, AND BACTERIAL RESISTANCE | WARNER-LAMBERT COMPANY | 2001-05-01 | — | — | US | claimed |
| WO-1998006691-A2 | LOW MOLECULAR WEIGHT DENDRITIC COMPOUNDS AS PHARMACEUTICAL AGENTS | WARNER-LAMBERT COMPANY (US) | 1998-02-19 | — | — | WO | claimed |
| US-6225352-B1 | USEFUL AS AGENTS IN THE TREATMENT OF CANCER, ALZHEIMERS DISEASE, THROMBOSIS, INFLAMMATORY DISEASES, AND BACTERIAL RESISTANCE | WARNER-LAMBERT COMPANY | 2001-05-01 | — | — | US | disclosed |
| WO-1998006691-A2 | LOW MOLECULAR WEIGHT DENDRITIC COMPOUNDS AS PHARMACEUTICAL AGENTS | WARNER-LAMBERT COMPANY (US) | 1998-02-19 | — | — | WO | disclosed |