Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.60 |
| ▸ | HPGD | P15428 | 6/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.60 |
| ▸ | IGLV6-57 | P01721 | 5/20 | 0.60 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.60 |
| ▸ | AR | P10275 | 3/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | GLA | P06280 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7907384 | 0.84 | ALDH1A1 (0.60) | ALDH1A1KDM4EHPGDHSD17B10IGLV6-57 | |
| SCHEMBL7920907 | 0.83 | KDM4E (0.53) | ALDH1A1KDM4EHPGDHSD17B10HTT | |
| SCHEMBL13726250 | 0.83 | ALDH1A1 (0.64) | ALDH1A1KDM4EHPGDHSD17B10IGLV6-57 | |
| SCHEMBL29408446 | 0.82 | ALDH1A1 (0.62) | ALDH1A1KDM4EHPGDHSD17B10ALDH2 | |
| SCHEMBL7920778 | 0.82 | ALDH1A1 (0.62) | ALDH1A1KDM4EHPGDHSD17B10ALDH2 | |
| SCHEMBL8835650 | 0.81 | IGLV6-57 (0.59) | ALDH1A1KDM4EHPGDHSD17B10IGLV6-57 | |
| SCHEMBL8835399 | 0.81 | IGLV6-57 (0.59) | ALDH1A1KDM4EHPGDHSD17B10IGLV6-57 | |
| SCHEMBL7907377 | 0.81 | IGLV6-57 (0.59) | ALDH1A1KDM4EHPGDHSD17B10IGLV6-57 | |
| SCHEMBL7914328 | 0.81 | MAOB (0.61) | ALDH1A1KDM4EHPGDHSD17B10ALDH2 | |
| SCHEMBL7914330 | 0.81 | ALDH1A1 (0.61) | ALDH1A1KDM4EHPGDHSD17B10ALDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6201087-B1 | POLYMERS WHICH CONTAIN COUMARIN OR QUINOLINONE DERIVATIVES AS PHOTOREACTIVE UNITS AS ORIENTING LAYERS FOR LIQUID CRYSTALS; PHOTOCHEMICAL STABILITY AND IMPROVED CONTRAST | ROLIC AG (CH) | 2001-03-13 | — | — | US | disclosed |
| EP-0783537-B1 | CUMARIN AND QUINOLINONE DERIVATIVES FOR PREPARING LIQUID CRYSTAL ORIENTATION LAYERS | ROLIC AG (CH) | 1999-12-01 | — | — | EP | disclosed |
| EP-0783537-A1 | CUMARIN AND QUINOLINONE DERIVATIVES FOR PREPARING LIQUID CRYSTAL ORIENTATION LAYERS | F. HOFFMANN-LA ROCHE AG (CH) | 1997-07-16 | — | — | EP | disclosed |
| WO-1996010049-A1 | CUMARIN AND QUINOLINONE DERIVATIVES FOR PREPARING LIQUID CRYSTAL ORIENTATION LAYERS | F. HOFFMANN-LA ROCHE AG (CH) | 1996-04-04 | — | — | WO | disclosed |