Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGLV6-57 | P01721 | 5/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.59 |
| ▸ | HPGD | P15428 | 5/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.59 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.58 |
| ▸ | AR | P10275 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | GLA | P06280 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8835399 | 0.89 | IGLV6-57 (0.59) | IGLV6-57ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL7907384 | 0.88 | ALDH1A1 (0.60) | IGLV6-57ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL7917181 | 0.81 | ALDH1A1 (0.60) | IGLV6-57ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL22501552 | 0.79 | KDM4E (0.74) | IGLV6-57ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL20537229 | 0.76 | KDM4E (0.78) | IGLV6-57ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL14176760 | 0.76 | KDM4E (1.00) | IGLV6-57ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL31281633 | 0.76 | KDM4E (1.00) | IGLV6-57ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL8834944 | 0.75 | IGLV6-57 (0.58) | IGLV6-57ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL22501672 | 0.75 | IGLV6-57 (1.00) | IGLV6-57ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL27788739 | 0.74 | ALDH1A1 (0.77) | IGLV6-57ALDH1A1KDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0783537-A1 | CUMARIN AND QUINOLINONE DERIVATIVES FOR PREPARING LIQUID CRYSTAL ORIENTATION LAYERS | F. HOFFMANN-LA ROCHE AG (CH) | 1997-07-16 | — | — | EP | disclosed |
| WO-1996010049-A1 | CUMARIN AND QUINOLINONE DERIVATIVES FOR PREPARING LIQUID CRYSTAL ORIENTATION LAYERS | F. HOFFMANN-LA ROCHE AG (CH) | 1996-04-04 | — | — | WO | disclosed |