Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 6/20 | 0.40 |
| ▸ | DPP4 | P27487 | 3/20 | 0.38 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
| ▸ | MAP4K1 | Q92918 | 2/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3786675 | 0.90 | CNR2 (0.41) | CACNA1HKLKB1SMN1; SMN2RAB9ATP53 | |
| SCHEMBL3796449 | 0.88 | CACNA1H (0.41) | CACNA1HKLKB1SMN1; SMN2RAB9ATP53 | |
| SCHEMBL7914426 | 0.84 | GRM5 (0.35) | DPP4KLKB1SMN1; SMN2LMNATP53 | |
| SCHEMBL7907025 | 0.83 | GAA (0.40) | CYP11B1CYP11B2SMN1; SMN2LMNATP53 | |
| SCHEMBL3795599 | 0.82 | HTR1A (0.42) | SMN1; SMN2RAB9AMAP4K1 | |
| SCHEMBL13869184 | 0.80 | CYP11B1 (0.36) | CACNA1HDPP4CYP11B1CYP11B2SMN1; SMN2 | |
| SCHEMBL7904612 | 0.79 | ALDH1A1 (0.41) | CACNA1HSMN1; SMN2RAB9AHPGD | |
| SCHEMBL3788894 | 0.78 | TRPV1 (0.39) | CACNA1HSMN1; SMN2RAB9A | |
| SCHEMBL4325189 | 0.77 | MELK (0.38) | SMN1; SMN2RAB9A | |
| SCHEMBL3469413 | 0.77 | GRM5 (0.42) | CACNA1HHCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010059838-A2 | PDE4 INHIBITORS SELECTIVE FOR THE LONG FORM OF PDE4 FOR TREATING INFLAMMATION AND AVOIDING SIDE EFFECTS | DECODE GENETICS EHF (IS) | 2010-05-27 | — | — | WO | disclosed |