Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.32 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.31 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methyl Alcohol SCHEMBL28206337 | 0.94 | ALDH1A1 (0.34) | ALDH1A1TSHRKDM4EMEN1LMNA | |
| SCHEMBL51449 | 0.94 | — | — | |
| SCHEMBL28181090 | 0.94 | ALDH1A1 (0.36) | ALDH1A1TSHRKDM4EMEN1LMNA | |
| SCHEMBL19305350 | 0.92 | ALDH1A1 (0.35) | ALDH1A1TSHRKDM4EMEN1LMNA | |
| Water SCHEMBL4304540 | 0.92 | ALDH1A1 (0.35) | ALDH1A1TSHRKDM4EMEN1LMNA | |
| Methoxymethane SCHEMBL28228821 | 0.91 | ALDH1A1 (0.32) | ALDH1A1TSHRKDM4EMEN1LMNA | |
| Acetone SCHEMBL28094281 | 0.91 | PKM (0.33) | ALDH1A1TSHRKDM4EMEN1LMNA | |
| Formic Acid SCHEMBL18555293 | 0.90 | ALDH1A1 (0.34) | ALDH1A1TSHRMAOB | |
| Water SCHEMBL28207794 | 0.90 | ALDH1A1 (0.34) | ALDH1A1TSHRMAOB | |
| Formaldehyde SCHEMBL28155252 | 0.90 | ALDH1A1 (0.34) | ALDH1A1TSHRMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110339841-A | Bimetal supported catalyst, preparation method and the method for preparing 2,5- dihydroxymethyl furans | 中国科学院宁波材料技术与工程研究所 | 2019-10-18 | — | — | CN | disclosed |
| CN-103797026-A | Bioproduction of aromatic chemicals from lignin-derived compounds | ALIGNA TECHNOLOGIES INC | 2014-05-14 | — | — | CN | disclosed |
| EP-2616481-A2 | BIOPRODUCTION OF AROMATIC CHEMICALS FROM LIGNIN-DERIVED COMPOUNDS | Aligna Technologies, Inc. (US) | 2013-07-24 | — | — | EP | disclosed |
| US-20130143304-A9 | LIGF-TYPE SYSTEMS FOR BIOCONVERSION OF LIGNIN-DERIVED COMPOUNDS | ALIGNA TECHNOLOGIES, INC. | 2013-06-06 | — | — | US | disclosed |
| US-20120202272-A1 | LIGE-TYPE SYSTEMS FOR BIOCONVERSION OF LIGNIN-DERIVED COMPOUNDS | ALIGNA TECHNOLOGIES, INC | 2012-08-09 | — | — | US | disclosed |
| US-20120202257-A1 | LIGE-TYPE ENZYMES FOR BIOCONVERSION OF LIGNIN-DERIVED COMPOUNDS | ALIGNA TECHNOLOGIES, INC. | 2012-08-09 | — | — | US | disclosed |
| US-20120202258-A1 | LIGE-TYPE TRANSFORMANTS FOR BIOCONVERSION OF LIGNIN-DERIVED COMPOUNDS | ALIGNA TECHNOLOGIES, INC. | 2012-08-09 | — | — | US | disclosed |
| US-20120196334-A1 | LIGF-TYPE ENZYMES FOR BIOCONVERSION OF LIGNIN-DERIVED COMPOUNDS | ALIGNA TECHNOLOGIES, INC. | 2012-08-02 | — | — | US | disclosed |
| US-20120196353-A1 | LIGF-TYPE SYSTEMS FOR BIOCONVERSION OF LIGNIN-DERIVED COMPOUNDS | CHATTERJEE RANJINI (US) | 2012-08-02 | — | — | US | disclosed |
| US-20120196335-A1 | LIGF-TYPE TRANSFORMANTS FOR BIOCONVERSION OF LIGNIN-DERIVED COMPOUNDS | ALIGNA TECHNOLOGIES, INC. | 2012-08-02 | — | — | US | disclosed |
| WO-2012036884-A2 | BIOPRODUCTION OF AROMATIC CHEMICALS FROM LIGNIN-DERIVED COMPOUNDS | ALIGNA TECHNOLOGIES, INC. (US) | 2012-03-22 | — | — | WO | disclosed |