SCHEMBL7917486

SCHEMBL7917486

COCC1CCC(CCc2ccc(-c3cc(F)c(C(F)(F)C(F)C(F)(F)F)c(F)c3)cc2)CC1

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 1/20 0.32
MAOB P27338 1/20 0.32
FFAR4 Q5NUL3 7/20 0.31
ACACB O00763 1/20 0.31
ACACA Q13085 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7911038 0.88 NAAA (0.33) GPR84
SCHEMBL7903767 0.87
SCHEMBL8834968 0.86 FFAR4 (0.32) GPR84FFAR4ACACBACACA
SCHEMBL7914104 0.86 ACACB (0.31) ACACBACACA
SCHEMBL7911750 0.85 MAOB (0.35) GPR84MAOB
SCHEMBL7911110 0.78 MAOB (0.35) MAOB
SCHEMBL8834778 0.76 GPR84 (0.32) GPR84MAOB
SCHEMBL7911955 0.75 SLC6A2 (0.30)
SCHEMBL7913738 0.75
SCHEMBL8834979 0.74 NAAA (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0640578-B2 Novel liquid crystalline compound having a 1,1,2,3,3,3,-hexafluoropropyl group and liquid crystal composition CHISSO CORP (JP) 2001-06-27 EP disclosed
EP-0640578-B1 Novel liquid crystalline compound having a 1,1,2,3,3,3,-hexafluoropropyl group and liquid crystal composition CHISSO CORP (JP) 1997-11-05 EP disclosed
EP-0640578-A1 Novel liquid crystalline compound having a 1,1,2,3,3,3,-hexafluoropropyl group and liquid crystal composition Chisso Corporation (JP) 1995-03-01 EP disclosed