Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 10/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | LTA4H | P09960 | 4/20 | 0.51 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.48 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7985189 | 0.85 | HRH3 (0.57) | HRH3MEN1KMT2ALTA4HPSMB1 | |
| SCHEMBL7996881 | 0.83 | LTA4H (0.65) | HRH3MEN1KMT2ALTA4HALDH1A1 | |
| SCHEMBL29204593 | 0.83 | HRH3 (0.62) | HRH3MEN1KMT2ALTA4HPSMB1 | |
| Hydrochloric Acid SCHEMBL29204587 | 0.82 | HRH3 (0.60) | HRH3MEN1KMT2ALTA4HPSMB1 | |
| SCHEMBL13493022 | 0.82 | HRH3 (0.57) | HRH3MEN1KMT2ALTA4HPSMB1 | |
| SCHEMBL13108495 | 0.80 | SLC6A4 (0.49) | HRH3LTA4HSLC6A4 | |
| SCHEMBL21663340 | 0.80 | LTA4H (0.67) | HRH3MEN1KMT2ALTA4HPSMB1 | |
| SCHEMBL7928593 | 0.79 | MEN1 (0.58) | HRH3MEN1KMT2ALTA4HALDH1A1 | |
| SCHEMBL19043467 | 0.79 | MEN1 (0.58) | HRH3MEN1KMT2ALTA4HALDH1A1 | |
| SCHEMBL19043542 | 0.78 | HRH3 (0.52) | HRH3MEN1KMT2ALTA4HPSMB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010039256-A1 | 2-ACYLAMINOPROPOANOL-TYPE GLUCOSYLCERAMIDE SYNTHASE INHIBITORS | GENZYME CORPORATION (US) | 2010-04-08 | — | — | WO | disclosed |