Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | LTA4H | P09960 | 2/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.51 |
| ▸ | HTR1A | P08908 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD1 | P21728 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19043467 | 1.00 | MEN1 (0.58) | MEN1KMT2AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL7924392 | 0.97 | KDM4E (0.56) | MEN1KMT2AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL7996881 | 0.87 | LTA4H (0.65) | MEN1KMT2AKDM4EALDH1A1LTA4H | |
| SCHEMBL13493022 | 0.81 | HRH3 (0.57) | MEN1KMT2AALDH1A1LTA4HHRH3 | |
| SCHEMBL7985189 | 0.81 | HRH3 (0.57) | MEN1KMT2AALDH1A1LTA4HHRH3 | |
| SCHEMBL29204593 | 0.79 | HRH3 (0.62) | MEN1KMT2AALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL8099708 | 0.79 | MEN1 (0.67) | MEN1KMT2AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL7917489 | 0.79 | HRH3 (0.55) | MEN1KMT2AALDH1A1LTA4HHRH3 | |
| Hydrochloric Acid SCHEMBL29204587 | 0.78 | HRH3 (0.60) | MEN1KMT2AALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL21663340 | 0.76 | LTA4H (0.67) | MEN1KMT2AALDH1A1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010039256-A1 | 2-ACYLAMINOPROPOANOL-TYPE GLUCOSYLCERAMIDE SYNTHASE INHIBITORS | GENZYME CORPORATION (US) | 2010-04-08 | — | — | WO | disclosed |