Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.32 |
| ▸ | WHR1 | P49842 | 1/20 | 0.31 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12921332 | 0.92 | IL1B (0.32) | PIM1PIM2 | |
| SCHEMBL373980 | 0.90 | PTGDR2 (0.31) | — | |
| SCHEMBL12209170 | 0.90 | PTGDR2 (0.31) | — | |
| SCHEMBL186973 | 0.87 | USP2 (0.37) | MAPK1 | |
| SCHEMBL7712191 | 0.82 | SYK (0.33) | MAPK1PIM1PIM2WHR1 | |
| SCHEMBL12921328 | 0.81 | ACHE (0.35) | PIM1PIM2 | |
| SCHEMBL15976825 | 0.80 | SLC18A3 (0.34) | MAPK1PIM1PIM2 | |
| SCHEMBL12921243 | 0.80 | PDE4D (0.33) | MAPK1WHR1 | |
| SCHEMBL187611 | 0.80 | GRM2 (0.35) | MAPK1WHR1 | |
| SCHEMBL12921237 | 0.80 | SRD5A1 (0.41) | MAPK1PIM1PIM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010097334-A1 | DRUG COMBINATIONS CONTAINING PDE4 INHIBITORS AND NSAIDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-09-02 | — | — | WO | disclosed |