SCHEMBL7917577

SCHEMBL7917577

COCOC1CCC(CCc2ccc(-c3ccc(C(F)(F)C(F)C(F)(F)F)cc3)cc2)CC1

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MAOB P27338 3/20 0.33
GPR84 Q9NQS5 1/20 0.31
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30
NAAA Q02083 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7913969 0.90 MAOB (0.32) MAOBGPR84
SCHEMBL7912197 0.87 ALDH1A1 (0.36) MAOBMEN1KMT2A
SCHEMBL7911038 0.86 NAAA (0.33) GPR84NAAA
SCHEMBL7911750 0.86 MAOB (0.35) MAOBGPR84
SCHEMBL7913753 0.83 HTR2C (0.31)
SCHEMBL7911815 0.82 MAOB (0.34) MAOBGPR84MEN1KMT2A
SCHEMBL8834979 0.81 NAAA (0.33) NAAA
SCHEMBL7913560 0.81 ALDH1A1 (0.36) MAOB
SCHEMBL7911110 0.79 MAOB (0.35) MAOB
SCHEMBL7914091 0.78 ALDH1A1 (0.35) MAOBMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0640578-B2 Novel liquid crystalline compound having a 1,1,2,3,3,3,-hexafluoropropyl group and liquid crystal composition CHISSO CORP (JP) 2001-06-27 EP disclosed
EP-0640578-B1 Novel liquid crystalline compound having a 1,1,2,3,3,3,-hexafluoropropyl group and liquid crystal composition CHISSO CORP (JP) 1997-11-05 EP disclosed
EP-0640578-A1 Novel liquid crystalline compound having a 1,1,2,3,3,3,-hexafluoropropyl group and liquid crystal composition Chisso Corporation (JP) 1995-03-01 EP disclosed