Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 7/20 | 0.47 |
| ▸ | CA2 | P00918 | 7/20 | 0.47 |
| ▸ | CA9 | Q16790 | 7/20 | 0.47 |
| ▸ | CA12 | O43570 | 5/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7913954 | 0.97 | ADRA1A (0.45) | ADRA1ATSHRLMNACYP1A2CYP2C19 | |
| SCHEMBL7903986 | 0.86 | ADRA1A (0.60) | ADRA1ATSHRLMNACYP1A2CYP2C19 | |
| SCHEMBL7903977 | 0.85 | ADRA1A (0.56) | ADRA1ATSHRLMNACYP1A2CYP2C19 | |
| SCHEMBL7913936 | 0.83 | GAA (0.48) | ADRA1ATSHRLMNACYP1A2CYP2C19 | |
| SCHEMBL7913958 | 0.81 | CA1 (0.41) | TSHRLMNACA1CA2CA9 | |
| SCHEMBL7912311 | 0.80 | ADRB2 (0.53) | TSHRCA1CA2CA9CA12 | |
| SCHEMBL7139259 | 0.80 | GAA (0.49) | ADRA1ATSHRCA1CA2CA9 | |
| SCHEMBL7914219 | 0.79 | KMT2A (0.43) | ADRA1ATSHRLMNACYP1A2CYP2C19 | |
| Hydrochloric Acid SCHEMBL11488060 | 0.77 | ADRB2 (0.50) | ADRA1ALMNACYP1A2CYP2C19GAA | |
| SCHEMBL9092422 | 0.76 | TSHR (0.58) | TSHRCA1CA2CA9CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6214882-B1 | Benzenesulphonamide derivatives, preparation thereof and therapeutical uses thereof | SYNTHELABO (FR) | 2001-04-10 | — | — | US | disclosed |