Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.61 |
| ▸ | GLA | P06280 | 5/20 | 0.61 |
| ▸ | GAA | P10253 | 5/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 3/20 | 0.51 |
| ▸ | MAOA | P21397 | 2/20 | 0.51 |
| ▸ | F2 | P00734 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | AR | P10275 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7917894 | 0.87 | ALDH1A1 (0.50) | KDM4EALDH1A1KMT2AGLAGAA | |
| SCHEMBL7914259 | 0.86 | AR (0.54) | KDM4EALDH1A1KMT2AGLAGAA | |
| SCHEMBL7920897 | 0.84 | KMT2A (0.55) | KDM4EALDH1A1KMT2AGLAGAA | |
| SCHEMBL7917178 | 0.84 | GBA1 (0.61) | KDM4EALDH1A1KMT2AGLAGAA | |
| SCHEMBL7920873 | 0.83 | GBA1 (0.60) | KDM4EALDH1A1KMT2AGLAGAA | |
| SCHEMBL7907574 | 0.83 | GBA1 (0.60) | KDM4EALDH1A1KMT2AGLAGAA | |
| SCHEMBL8834993 | 0.81 | KDM4E (0.59) | KDM4EALDH1A1KMT2AGLAGAA | |
| SCHEMBL7920875 | 0.81 | GBA1 (0.63) | KDM4EALDH1A1KMT2AGLAGAA | |
| SCHEMBL7907388 | 0.80 | ALDH1A1 (0.60) | KDM4EALDH1A1KMT2AGLAGAA | |
| SCHEMBL4386227 | 0.80 | KDM4E (0.79) | KDM4EALDH1A1KMT2AGLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6201087-B1 | POLYMERS WHICH CONTAIN COUMARIN OR QUINOLINONE DERIVATIVES AS PHOTOREACTIVE UNITS AS ORIENTING LAYERS FOR LIQUID CRYSTALS; PHOTOCHEMICAL STABILITY AND IMPROVED CONTRAST | ROLIC AG (CH) | 2001-03-13 | — | — | US | disclosed |
| EP-0783537-A1 | CUMARIN AND QUINOLINONE DERIVATIVES FOR PREPARING LIQUID CRYSTAL ORIENTATION LAYERS | F. HOFFMANN-LA ROCHE AG (CH) | 1997-07-16 | — | — | EP | disclosed |
| WO-1996010049-A1 | CUMARIN AND QUINOLINONE DERIVATIVES FOR PREPARING LIQUID CRYSTAL ORIENTATION LAYERS | F. HOFFMANN-LA ROCHE AG (CH) | 1996-04-04 | — | — | WO | disclosed |