SCHEMBL7917841

SCHEMBL7917841

CC(C)(C)c1c(O)c(C(C)(C)C)c(C(C)(C)C)c(C(=O)O)c1-c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GLRA3 O75311 1/20 0.41
GLRB P48167 1/20 0.41
PKM P14618 1/20 0.40
HKDC1 Q2TB90 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
HNF4A P41235 1/20 0.39
LMNA P02545 2/20 0.37
DHODH Q02127 2/20 0.37
PDE10A Q9Y233 1/20 0.37
KMT2A Q03164 3/20 0.37
MEN1 O00255 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.36
PDE4A P27815 2/20 0.36
PDE4B Q07343 2/20 0.36
PDE4C Q08493 2/20 0.36
PDE4D Q08499 2/20 0.36
KDM4E B2RXH2 1/20 0.36
RCE1 Q9Y256 1/20 0.36
FABP3 P05413 4/20 0.35
FABP4 P15090 4/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30400599 0.88 KDM4E (0.37) GLRA3GLRBPKMHKDC1L3MBTL1
SCHEMBL28133115 0.88 LMNA (0.40) GLRA3GLRBPKMHKDC1L3MBTL1
SCHEMBL27987654 0.83 GRM6 (0.45) PKMHKDC1L3MBTL1LMNAKMT2A
SCHEMBL6516655 0.79 SLC37A4 (0.42) LMNAKDM4EPPARG
SCHEMBL29598323 0.78 BID (0.42) KDM4EPPARG
SCHEMBL10591491 0.77 BID (0.44) KDM4EPPARG
SCHEMBL17599778 0.73 BCL2 (0.32) PKMHKDC1L3MBTL1FABP3FABP4
SCHEMBL11876688 0.73 GLRA3 (0.45) GLRA3GLRBPKMHKDC1L3MBTL1
SCHEMBL30272446 0.73 GLRA3 (0.45) GLRA3GLRBPKMHKDC1L3MBTL1
SCHEMBL7781053 0.72 GLRA3 (0.66) GLRA3GLRBPKMHKDC1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0410970-B1 REACTIVE HINDERED AMINE LIGHT STABILIZERS ATOCHEM NORTH AMERICA ELF (US) 1996-08-14 EP claimed
EP-1155098-A1 LIQUID CRYSTALLINE SUBSTANCE MIXTURES BASF AKTIENGESELLSCHAFT (DE) 2001-11-21 EP disclosed
WO-2000047694-A1 LIQUID CRYSTALLINE SUBSTANCE MIXTURES BASF AKTIENGESELLSCHAFT (DE) 2000-08-17 WO disclosed
EP-0019578-A1 Piperidine derivatives, process for preparing them and polymer compositions containing them Chimosa Chimica Organica S.p.A. (IT) 1980-11-26 EP disclosed