Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL628806 | 0.84 | MEN1 (0.41) | — | |
| Hydrochloric Acid SCHEMBL629209 | 0.83 | MEN1 (0.41) | — | |
| SCHEMBL7869097 | 0.83 | NPC1 (0.56) | — | |
| Decarboxylated Derivative SCHEMBL628807 | 0.81 | FNTA (0.41) | — | |
| SCHEMBL629652 | 0.80 | FNTA (0.44) | — | |
| SCHEMBL7870257 | 0.80 | MEN1 (0.47) | SMN1; SMN2 | |
| Decarboxylated Derivative SCHEMBL629210 | 0.80 | FNTA (0.41) | — | |
| SCHEMBL8590418 | 0.78 | FNTA (0.65) | — | |
| SCHEMBL628906 | 0.78 | FNTA (0.43) | — | |
| SCHEMBL7921429 | 0.78 | FNTA (0.64) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6221865-B1 | INHIBITORS OF PROTEIN FARNESYLTRANSFERASE AND PROTEIN GERANYLGERANYLTRANSFERASE. | UNIVERSITY OF PITTSBURGH | 2001-04-24 | — | — | US | disclosed |