Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL629209 | 0.99 | MEN1 (0.41) | MEN1KMT2A | |
| SCHEMBL629652 | 0.88 | FNTA (0.44) | — | |
| SCHEMBL7869097 | 0.84 | NPC1 (0.56) | MEN1KMT2A | |
| SCHEMBL7917853 | 0.84 | ALDH1A1 (0.41) | — | |
| Decarboxylated Derivative SCHEMBL628807 | 0.82 | FNTA (0.41) | — | |
| SCHEMBL7870257 | 0.81 | MEN1 (0.47) | MEN1KMT2A | |
| Decarboxylated Derivative SCHEMBL629210 | 0.81 | FNTA (0.41) | — | |
| SCHEMBL631089 | 0.80 | ALDH1A1 (0.52) | MEN1KMT2A | |
| SCHEMBL7870317 | 0.80 | FNTA (0.61) | — | |
| SCHEMBL628805 | 0.79 | BACE1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0986384-B1 | INHIBITORS OF PROTEIN ISOPRENYL TRANSFERASES | UNIV PITTSBURGH (US) | 2012-02-22 | — | — | EP | disclosed |
| US-6310095-B1 | INHIBITING OR TREATING CANCER, TREATING INTIMAL HYPERPLASIA ASSOCIATED WITH RESTENOSIS AND ATHEROSCLEROSIS, INHIBITING POST-TRANSLATIONAL MODIFICATION OF ONCOGENIC RAS PROTEIN BY PROTEIN FARNESYLTRANSFERASE AND/OR GERANYLGERANYLTRANSFERASE | UNIVERSITY OF PITTSBURGH | 2001-10-30 | — | — | US | disclosed |