SCHEMBL628906

SCHEMBL628906

CCC(CCC1CCCCC1)S(=O)(=O)NCc1ccc(C(=O)OC)c(-c2ccccc2C)c1

nearest known ligand 0.47

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FNTA P49354 1/20 0.43
FNTB P49356 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7869135 0.91 FNTA (0.45) FNTAFNTB
SCHEMBL7917853 0.78 ALDH1A1 (0.41)
Decarboxylated Derivative SCHEMBL628807 0.77 FNTA (0.41) FNTAFNTB
Decarboxylated Derivative SCHEMBL629210 0.76 FNTA (0.41) FNTAFNTB
SCHEMBL628806 0.76 MEN1 (0.41)
SCHEMBL7869010 0.75 FNTA (0.41) FNTAFNTB
SCHEMBL628907 0.75 FNTA (0.49) FNTAFNTB
SCHEMBL10193883 0.75 FNTA (0.52) FNTAFNTB
SCHEMBL7905224 0.75 FNTA (0.41) FNTAFNTB
Hydrochloric Acid SCHEMBL629209 0.75 MEN1 (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0986384-B1 INHIBITORS OF PROTEIN ISOPRENYL TRANSFERASES UNIV PITTSBURGH (US) 2012-02-22 EP disclosed
US-6310095-B1 INHIBITING OR TREATING CANCER, TREATING INTIMAL HYPERPLASIA ASSOCIATED WITH RESTENOSIS AND ATHEROSCLEROSIS, INHIBITING POST-TRANSLATIONAL MODIFICATION OF ONCOGENIC RAS PROTEIN BY PROTEIN FARNESYLTRANSFERASE AND/OR GERANYLGERANYLTRANSFERASE UNIVERSITY OF PITTSBURGH 2001-10-30 US disclosed