SCHEMBL7917899

SCHEMBL7917899

C=CC(=O)Oc1ccc2c(-c3ccccc3)cc(=O)oc2c1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA9 Q16790 2/20 0.72
ESR1 P03372 1/20 0.66
ALDH1A1 P00352 10/20 0.65
HPGD P15428 9/20 0.65
SMN1; SMN2 Q16637 1/20 0.65
KDM4E B2RXH2 5/20 0.64
KMT2A Q03164 3/20 0.64
HTT P42858 2/20 0.64
MAPT P10636 1/20 0.64
L3MBTL1 Q9Y468 1/20 0.64
USP2 O75604 1/20 0.62
MAOB P27338 2/20 0.59
AKR1B1 P15121 2/20 0.58
CA12 O43570 1/20 0.58
ALDH2 P05091 1/20 0.58
MAOA P21397 1/20 0.58
HSD17B3 P37058 1/20 0.58
SORD Q00796 1/20 0.58
RECQL P46063 2/20 0.55
LMNA P02545 2/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7917698 0.85 ALDH1A1 (0.65) CA9ESR1ALDH1A1HPGDSMN1; SMN2
SCHEMBL7914254 0.83 CA9 (0.69) CA9ESR1ALDH1A1HPGDSMN1; SMN2
SCHEMBL8171067 0.80 MAOB (0.70) CA9ESR1ALDH1A1HPGDSMN1; SMN2
SCHEMBL12729881 0.80 ESR1 (1.00) CA9ESR1ALDH1A1HPGDSMN1; SMN2
Acrylic Acid SCHEMBL29007733 0.80 CA9 (0.82) CA9ALDH1A1HPGDSMN1; SMN2KDM4E
SCHEMBL31120325 0.79 ALDH1A1 (0.72) CA9ALDH1A1HPGDKDM4EKMT2A
SCHEMBL1459402 0.79 ALDH1A1 (0.72) CA9ALDH1A1HPGDKDM4EKMT2A
SCHEMBL21648257 0.79 MAOB (0.71) CA9ESR1ALDH1A1HPGDSMN1; SMN2
SCHEMBL12227473 0.79 ALDH1A1 (0.68) CA9ESR1ALDH1A1HPGDSMN1; SMN2
SCHEMBL14997043 0.79 ALDH1A1 (0.68) CA9ESR1ALDH1A1HPGDSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107936172-B Preparation method of coumarin polymer semiconductor laser material 无锡佶达德光电子技术有限公司 2023-04-28 CN claimed
CN-107987209-B Coumarin polymer semiconductor laser material and application thereof 无锡佶达德光电子技术有限公司 2023-05-02 CN disclosed
CN-107936172-B Preparation method of coumarin polymer semiconductor laser material 无锡佶达德光电子技术有限公司 2023-04-28 CN disclosed
US-6201087-B1 POLYMERS WHICH CONTAIN COUMARIN OR QUINOLINONE DERIVATIVES AS PHOTOREACTIVE UNITS AS ORIENTING LAYERS FOR LIQUID CRYSTALS; PHOTOCHEMICAL STABILITY AND IMPROVED CONTRAST ROLIC AG (CH) 2001-03-13 US disclosed
EP-0783537-A1 CUMARIN AND QUINOLINONE DERIVATIVES FOR PREPARING LIQUID CRYSTAL ORIENTATION LAYERS F. HOFFMANN-LA ROCHE AG (CH) 1997-07-16 EP disclosed
WO-1996010049-A1 CUMARIN AND QUINOLINONE DERIVATIVES FOR PREPARING LIQUID CRYSTAL ORIENTATION LAYERS F. HOFFMANN-LA ROCHE AG (CH) 1996-04-04 WO disclosed