Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.65 |
| ▸ | HPGD | P15428 | 8/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | USP2 | O75604 | 1/20 | 0.63 |
| ▸ | MAOB | P27338 | 1/20 | 0.60 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | ESR1 | P03372 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | TNF | P01375 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8835114 | 0.88 | ALDH1A1 (0.65) | ALDH1A1HPGDSMN1; SMN2KMT2AUSP2 | |
| SCHEMBL7917899 | 0.85 | CA9 (0.72) | ALDH1A1HPGDSMN1; SMN2KMT2AUSP2 | |
| SCHEMBL7917987 | 0.84 | ALDH1A1 (0.68) | ALDH1A1HPGDSMN1; SMN2KMT2AUSP2 | |
| SCHEMBL12886696 | 0.84 | ALDH1A1 (0.77) | ALDH1A1HPGDSMN1; SMN2KMT2AUSP2 | |
| SCHEMBL7920889 | 0.82 | KMT2A (0.61) | ALDH1A1HPGDSMN1; SMN2KMT2AMAOB | |
| SCHEMBL30837680 | 0.82 | KMT2A (0.61) | ALDH1A1HPGDSMN1; SMN2KMT2AMAOB | |
| SCHEMBL8171067 | 0.81 | MAOB (0.70) | ALDH1A1HPGDSMN1; SMN2KMT2AUSP2 | |
| SCHEMBL7915805 | 0.80 | AGER (0.67) | MAOB | |
| SCHEMBL12722470 | 0.79 | MAOB (0.71) | ALDH1A1HPGDSMN1; SMN2KMT2AUSP2 | |
| SCHEMBL21630150 | 0.79 | HPGD (1.00) | ALDH1A1HPGDSMN1; SMN2KMT2AUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6201087-B1 | POLYMERS WHICH CONTAIN COUMARIN OR QUINOLINONE DERIVATIVES AS PHOTOREACTIVE UNITS AS ORIENTING LAYERS FOR LIQUID CRYSTALS; PHOTOCHEMICAL STABILITY AND IMPROVED CONTRAST | ROLIC AG (CH) | 2001-03-13 | — | — | US | disclosed |