Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.68 |
| ▸ | HPGD | P15428 | 8/20 | 0.68 |
| ▸ | USP2 | O75604 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | MAOB | P27338 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | TNF | P01375 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.53 |
| ▸ | ESR1 | P03372 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7914254 | 0.85 | CA9 (0.69) | ALDH1A1HPGDUSP2KMT2ASMN1; SMN2 | |
| SCHEMBL7917698 | 0.84 | ALDH1A1 (0.65) | ALDH1A1HPGDUSP2KMT2ASMN1; SMN2 | |
| SCHEMBL7920778 | 0.84 | ALDH1A1 (0.62) | ALDH1A1HPGDKMT2ASMN1; SMN2MAOB | |
| SCHEMBL29408446 | 0.84 | ALDH1A1 (0.62) | ALDH1A1HPGDKMT2ASMN1; SMN2MAOB | |
| SCHEMBL12886696 | 0.83 | ALDH1A1 (0.77) | ALDH1A1HPGDUSP2KMT2ASMN1; SMN2 | |
| SCHEMBL7917198 | 0.83 | ALDH1A1 (0.67) | ALDH1A1HPGDKMT2AKDM4ELMNA | |
| SCHEMBL8835114 | 0.82 | ALDH1A1 (0.65) | ALDH1A1HPGDUSP2KMT2ASMN1; SMN2 | |
| SCHEMBL17084634 | 0.82 | ALDH1A1 (0.57) | ALDH1A1HPGDKMT2AMAOBKDM4E | |
| SCHEMBL12722470 | 0.81 | MAOB (0.71) | ALDH1A1HPGDUSP2KMT2ASMN1; SMN2 | |
| SCHEMBL28722650 | 0.81 | MAOB (0.71) | ALDH1A1HPGDUSP2KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6201087-B1 | POLYMERS WHICH CONTAIN COUMARIN OR QUINOLINONE DERIVATIVES AS PHOTOREACTIVE UNITS AS ORIENTING LAYERS FOR LIQUID CRYSTALS; PHOTOCHEMICAL STABILITY AND IMPROVED CONTRAST | ROLIC AG (CH) | 2001-03-13 | — | — | US | disclosed |
| EP-0783537-B1 | CUMARIN AND QUINOLINONE DERIVATIVES FOR PREPARING LIQUID CRYSTAL ORIENTATION LAYERS | ROLIC AG (CH) | 1999-12-01 | — | — | EP | disclosed |