Sugi Predict

Sugi Predict / Compounds / Dimethylamine

Dimethylamine

Dimethylamine

SCHEMBL7918009

CCc1cc(C)ccc1S(=O)(=O)O.CNC

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ RAPGEF4 Q8WZA2 1/20 0.41
▸ HSD17B10 Q99714 3/20 0.39
▸ LMNA P02545 1/20 0.39
▸ HPGD P15428 1/20 0.39
▸ HIF1A Q16665 1/20 0.39
▸ GAA P10253 3/20 0.39
▸ ALDH1A1 P00352 3/20 0.39
▸ KMT2A Q03164 2/20 0.39
▸ POLB P06746 2/20 0.39
▸ MEP1B Q16820 2/20 0.39
▸ KDM4E B2RXH2 1/20 0.39
▸ MEN1 O00255 1/20 0.39
▸ MAPT P10636 1/20 0.39
▸ RECQL P46063 1/20 0.39
▸ CASP6 P55212 1/20 0.39
▸ ELAVL1 Q15717 1/20 0.39
▸ TDP1 Q9NUW8 1/20 0.39
▸ L3MBTL1 Q9Y468 1/20 0.39
▸ TSHR P16473 2/20 0.38
▸ CASP1 P29466 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1607815 0.94 RAPGEF4 (0.44) RAPGEF4HSD17B10LMNAHPGDHIF1A
SCHEMBL30236538 0.94 RAPGEF4 (0.44) RAPGEF4HSD17B10LMNAHPGDHIF1A
Water SCHEMBL27145442 0.93 RAPGEF4 (0.43) RAPGEF4HSD17B10LMNAHPGDHIF1A
SCHEMBL1180196 0.87 GAA (0.41) RAPGEF4HSD17B10LMNAHPGDHIF1A
SCHEMBL30716894 0.87 AMY1A (0.44) RAPGEF4HSD17B10LMNAHPGDHIF1A
SCHEMBL30823619 0.87 GAA (0.41) RAPGEF4HSD17B10LMNAHPGDHIF1A
SCHEMBL14991279 0.87 AMY1A (0.44) RAPGEF4HSD17B10LMNAHPGDHIF1A
SCHEMBL3339137 0.86 HSD17B10 (0.39) RAPGEF4HSD17B10LMNAHPGDHIF1A
Ammonia Solution, Strong SCHEMBL28142626 0.84 HSD17B10 (0.38) RAPGEF4HSD17B10LMNAHPGDHIF1A
SCHEMBL816601 0.84 GAA (0.39) RAPGEF4HSD17B10LMNAHPGDHIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0897379-B1 PROCESS FOR CONVERTING A GEMINALLY SUBSTITUTED CYCLOPENTADIENE DSM NV (NL) 2001-10-31 — — EP disclosed
US-6137019-A Process for converting a geminally substituted cyclopentadiene DSM N.V. (NL) 2000-10-24 — — US disclosed
US-6124488-A ACTIVE AS CATALYST COMPONENTS, IN PARTICULAR FOR THE POLYMERIZATION OF OLEFINS. DSM N.V. (NL) 2000-09-26 — — US disclosed
US-6072067-A Cyclopentadiene compound substituted with a hetero atom-containing group DSM N.V. (NL) 2000-06-06 — — US disclosed
EP-0805142-B1 Cyclopentadiene compound substituted with a hetero atom-containing group DSM NV (NL) 1999-03-24 — — EP disclosed
EP-0900195-A1 CYCLOPENTADIENE COMPOUND SUBSTITUTED WITH BRANCHED ALKYL GROUPS DSM N.V. (NL) 1999-03-10 — — EP disclosed
EP-0897379-A1 PROCESS FOR CONVERTING A GEMINALLY SUBSTITUTED CYCLOPENTADIENE DSM N.V. (NL) 1999-02-24 — — EP disclosed
WO-1997042162-A1 CYCLOPENTADIENE COMPOUND SUBSTITUTED WITH BRANCHED ALKYL GROUPS DSM N.V. (NL) 1997-11-13 — — WO disclosed
WO-1997042149-A1 CYCLOPENTADIENE COMPOUND SUBSTITUTED WITH TERTIARY GROUPS DSM N.V. (NL) 1997-11-13 — — WO disclosed
WO-1997042148-A1 CYCLOPENTADIENE COMPOUND SUBSTITUTED WITH CYCLIC GROUPS DSM N.V. (NL) 1997-11-13 — — WO disclosed
WO-1997042158-A1 SYNTHESIS OF A SUBSTITUTED CYCLOPENTADIENE COMPOUND DSM N.V. (NL) 1997-11-13 — — WO disclosed
WO-1997042145-A1 PROCESS FOR CONVERTING A GEMINALLY SUBSTITUTED CYCLOPENTADIENE DSM N.V. (NL) 1997-11-13 — — WO disclosed
EP-0805142-A1 Cyclopentadiene compound substituted with a hetero atom-containing group DSM N.V. (NL) 1997-11-05 — — EP disclosed