SCHEMBL7918232

SCHEMBL7918232

CCCC(CC1CCCCC1)C(c1ccc(C(=O)NC(CCSC)C(=O)O)c(-c2ccccc2C)c1)P(=O)=O

nearest known ligand 0.62

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FNTA P49354 2/20 0.59
FNTB P49356 2/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL628618 0.86 FNTA (0.59) FNTAFNTB
SCHEMBL629726 0.85 FNTA (0.63) FNTAFNTB
SCHEMBL7870229 0.85 FNTA (0.59) FNTAFNTB
SCHEMBL6625521 0.85 FNTA (0.58) FNTAFNTB
SCHEMBL7908505 0.85 FNTA (0.58) FNTAFNTB
SCHEMBL7870168 0.85 FNTA (0.62) FNTAFNTB
SCHEMBL6629271 0.84 FNTA (0.60) FNTAFNTB
SCHEMBL7918601 0.84 FNTA (0.38) FNTAFNTB
SCHEMBL7921813 0.84 FNTA (0.63) FNTAFNTB
SCHEMBL630142 0.84 FNTA (0.59) FNTAFNTB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1998050030-A1 INHIBITORS OF PROTEIN ISOPRENYL TRANSFERASES UNIVERSITY OF PITTSBURGH (US) 1998-11-12 WO claimed
US-6221865-B1 INHIBITORS OF PROTEIN FARNESYLTRANSFERASE AND PROTEIN GERANYLGERANYLTRANSFERASE. UNIVERSITY OF PITTSBURGH 2001-04-24 US disclosed