SCHEMBL7918601

SCHEMBL7918601

CCCC(CC1CCCCC1)C(c1ccc(C(=O)O)c(-c2ccccc2C)c1)P(=O)=O

nearest known ligand 0.41

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FNTA P49354 1/20 0.38
FNTB P49356 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7921832 0.90 FNTA (0.37) FNTAFNTB
SCHEMBL7918232 0.84 FNTA (0.59) FNTAFNTB
SCHEMBL6625288 0.74 FNTA (0.42) FNTAFNTB
SCHEMBL7904108 0.73 FNTA (0.41) FNTAFNTB
SCHEMBL7906204 0.72
SCHEMBL7918444 0.71 FNTA (0.40) FNTAFNTB
SCHEMBL629649 0.71 FNTA (0.37) FNTAFNTB
SCHEMBL7897407 0.70 FNTA (0.40) FNTAFNTB
SCHEMBL7897412 0.70 FNTA (0.40) FNTAFNTB
SCHEMBL7897411 0.70 FNTA (0.40) FNTAFNTB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6221865-B1 INHIBITORS OF PROTEIN FARNESYLTRANSFERASE AND PROTEIN GERANYLGERANYLTRANSFERASE. UNIVERSITY OF PITTSBURGH 2001-04-24 US disclosed