Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 19/20 | 0.60 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.46 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.46 |
| ▸ | CCR7 | P32248 | 1/20 | 0.46 |
| ▸ | CCR2 | P41597 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5208404 | 0.84 | CCR5 (0.68) | CCR5 | |
| SCHEMBL7918243 | 0.84 | CCR2 (0.65) | CCR5CCR2 | |
| SCHEMBL7684671 | 0.82 | CCR5 (0.60) | CCR5CXCR3CXCR5CCR2 | |
| SCHEMBL5209854 | 0.77 | CCR5 (0.68) | CCR5 | |
| Hydrochloric Acid SCHEMBL5208149 | 0.76 | CCR5 (0.98) | CCR5CXCR3CXCR5CCR7CCR2 | |
| SCHEMBL5206072 | 0.75 | CCR5 (0.65) | CCR5 | |
| SCHEMBL3026537 | 0.75 | CCR2 (0.77) | CCR5CCR2 | |
| SCHEMBL5208241 | 0.75 | CCR2 (0.67) | CCR5CCR2 | |
| SCHEMBL5241768 | 0.75 | CCR2 (0.67) | CCR5CCR2 | |
| SCHEMBL5209111 | 0.75 | CCR5 (0.74) | CCR5CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6172061-B1 | AIDS THERAPY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-01-09 | — | — | US | disclosed |