Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MDM4 | O15151 | 1/20 | 0.49 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.49 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.49 |
| ▸ | ITGAV | P06756 | 1/20 | 0.49 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.49 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | USP30 | Q70CQ3 | 5/20 | 0.46 |
| ▸ | MC4R | P32245 | 1/20 | 0.46 |
| ▸ | MC5R | P33032 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL290267 | 1.00 | NPC1 (0.50) | NPC1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL16213507 | 0.85 | KDM4E (0.48) | NPC1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL16213504 | 0.85 | KDM4E (0.48) | NPC1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL1766005 | 0.84 | TGM2 (0.50) | ITGB3TGM2ALDH1A1 | |
| SCHEMBL7918402 | 0.84 | MEN1 (0.51) | MEN1KMT2AHDAC1HSD17B10MC4R | |
| SCHEMBL7860939 | 0.84 | MEN1 (0.51) | MEN1KMT2AHDAC1HSD17B10MC4R | |
| SCHEMBL7860945 | 0.84 | MEN1 (0.51) | MEN1KMT2AHDAC1HSD17B10MC4R | |
| SCHEMBL28896050 | 0.83 | MC4R (0.60) | MEN1KMT2AHDAC1HSD17B10MC4R | |
| SCHEMBL676271 | 0.82 | HDAC1 (0.51) | CYP3A4CYP2D6CYP2C9CYP2C19MEN1 | |
| SCHEMBL10583019 | 0.82 | HDAC1 (0.51) | CYP3A4CYP2D6CYP2C9CYP2C19MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-219675843-U | Periodontal disease detection device | 浙江中医药大学 | 2023-09-12 | — | — | CN | disclosed |
| US-20200289651-A1 | SUSTAINED-RELEASE DRUG CARRIER COMPOSITION | KREOS CAPITAL VI (EXPERT FUND) L.P. (JE) | 2020-09-17 | — | — | US | disclosed |
| US-10682412-B2 | Sustained-release drug carrier composition | POLYPID LTD. (IL) | 2020-06-16 | — | — | US | disclosed |
| CN-109988228-A | A kind of astragalus mongolicus pathogenesis-related proteins and its crystal, growing method and purposes | 山西中医药大学 | 2019-07-09 | — | — | CN | disclosed |
| US-10337047-B2 | Assay for early detection of a disease using a magnetic nanoparticle biosensor | Alfaisal University (SA) | 2019-07-02 | — | — | US | disclosed |
| US-20190070298-A1 | SUSTAINED-RELEASE DRUG CARRIER COMPOSITION | KREOS CAPITAL VI (EXPERT FUND) LP (JE) | 2019-03-07 | — | — | US | disclosed |
| EP-3111800-B1 | DEVICE FOR IDENTIFYING ORAL CONDITIONS | COLGATE PALMOLIVE CO (US) | 2018-11-21 | — | — | EP | disclosed |
| US-10105443-B2 | Sustained-release drug carrier composition | POLYPID LTD. (IL) | 2018-10-23 | — | — | US | disclosed |
| US-9700395-B2 | Device for identifying oral conditions | COLGATE-PALMOLIVE COMPANY (US) | 2017-07-11 | — | — | US | disclosed |
| US-20170116665-A1 | SMART ORAL HYGIENE AID | ALZAHRANI ABDULRAHMAN OBAID (US) | 2017-04-27 | — | — | US | disclosed |
| US-6143506-A | MONITORING ORAL DISEASES BY COLLECTING GINGIVAL CREVICULAR FLUID, PERI-IMPLANT SULCULAR FLUID, SALIVA OR MOUTHRINSE SAMPLE, CONTACTING WITH MOLECULE WHICH RECOGNIZES MAMMALIAN MATRIX METALLOPROTEINASE-13, DETECTING PRESENCE OF ENZYME | THE RESEARCH FOUNDATION OF STATE OF NY (US) | 2000-11-07 | — | — | US | disclosed |
| EP-0832119-B1 | ANTI-FUNGAL AND ANTI-BACTERIAL HISTATIN-BASED PEPTIDES | PERIODONTIX INC (US) | 2000-09-20 | — | — | EP | disclosed |
| US-5736341-A | USING A MONOCLONAL ANTIBODY WHICH RECOGNIZES A TISSUE DESTRUCTIVE ACTIVE FORM OF MAMMALIAN MATRIX METALLOPROTEINASE-8 IN ORAL FLUIDS; IMMUNOASSAY | OY MEDIX BIOCHEMICA AB (FI) | 1998-04-07 | — | — | US | disclosed |
| WO-1997050046-A2 | ASSESSMENT, PREVENTION AND TREATMENT OF ORAL DISEASE | THE ORALIFE GROUP, INC. (CA) | 1997-12-31 | — | — | WO | disclosed |
| CN-1158551-A | Biological control of insects | UNIV TROBE (AU) | 1997-09-03 | — | — | CN | disclosed |
| EP-0777859-A1 | METHODS AND TEST KITS FOR SPECIFIC AND SENSITIVE DIAGNOSING OF PERIODONTAL DISEASES | OY MEDIX BIOCHEMICA AB (FI) | 1997-06-11 | — | — | EP | disclosed |
| WO-1996007103-A1 | METHODS AND TEST KITS FOR SPECIFIC AND SENSITIVE DIAGNOSING OF PERIODONTAL DISEASES | OY MEDIX BIOCHEMICA AB (FI) | 1996-03-07 | — | — | WO | disclosed |
| US-5223403-A | Device for diagnosing periodontal disease | UNIVERSITY OF MICHIGAN (US) | 1993-06-29 | — | — | US | disclosed |
| EP-0523079-A1 | SYSTEM FOR DIAGNOSING PERIODONTAL DISEASE | THE UNIVERSITY OF MICHIGAN (US) | 1993-01-20 | — | — | EP | disclosed |
| WO-1991014000-A1 | SYSTEM FOR DIAGNOSING PERIODONTAL DISEASE | THE UNIVERSITY OF MICHIGAN (US) | 1991-09-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10105443-B2 | Sustained-release drug carrier composition | LIPA, LIPC, ABCB11 | NPC1 84/4885CYP1A2 241/4885CYP3A4 422/4885 |
| US-10682412-B2 | Sustained-release drug carrier composition | LIPA, LIPC, ABCB11 | NPC1 84/4885CYP1A2 241/4885CYP3A4 422/4885 |
| US-20200289651-A1 | SUSTAINED-RELEASE DRUG CARRIER COMPOSITION | LIPA, LIPC, ABCB11 | NPC1 84/4885CYP1A2 241/4885CYP3A4 422/4885 |
| US-20190070298-A1 | SUSTAINED-RELEASE DRUG CARRIER COMPOSITION | LIPA, LIPC, ABCB11 | NPC1 84/4885CYP1A2 241/4885CYP3A4 422/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.