Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7918649 | 0.94 | MAPT (0.54) | MAPTKMT2AGAALMNAMEN1 | |
| SCHEMBL7904825 | 0.89 | MAPT (0.63) | MAPTKMT2AGAALMNAMEN1 | |
| SCHEMBL7913404 | 0.89 | MAPT (0.50) | MAPTKMT2AGAALMNAMEN1 | |
| SCHEMBL7904894 | 0.83 | MAPT (0.62) | MAPTKMT2AGAALMNAMEN1 | |
| SCHEMBL7912149 | 0.83 | THRB (0.50) | MAPTKMT2AGAALMNAMEN1 | |
| SCHEMBL7918610 | 0.81 | MEN1 (0.56) | MAPTKMT2AGAALMNAMEN1 | |
| SCHEMBL7918641 | 0.81 | MAPT (0.45) | MAPTKMT2AGAALMNAMEN1 | |
| SCHEMBL7905044 | 0.79 | MAPT (0.55) | MAPTKMT2AGAALMNAMEN1 | |
| SCHEMBL7913390 | 0.79 | MAPT (0.56) | MAPTKMT2AGAALMNAMEN1 | |
| SCHEMBL7915059 | 0.79 | NPSR1 (0.52) | MAPTKMT2AGAALMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207666-B1 | TREATING PRECANCEROUS LESIONS BY ADMINISTERING 4-PHENYLPHTHALAZINE DERIVATIVE | CELL PATHWAYS, INC. | 2001-03-27 | — | — | US | disclosed |