Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP2 | P42575 | 1/20 | 0.56 |
| ▸ | NAAA | Q02083 | 1/20 | 0.53 |
| ▸ | EPHX1 | P07099 | 7/20 | 0.52 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.51 |
| ▸ | FAAH | O00519 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21768078 | 0.96 | CASP2 (0.56) | CASP2NAAAEPHX1DNM1FAAH | |
| SCHEMBL1258600 | 0.95 | DNM1 (0.50) | CASP2NAAAEPHX1DNM1FAAH | |
| SCHEMBL29936144 | 0.91 | DNM1 (0.48) | CASP2NAAAEPHX1DNM1FAAH | |
| SCHEMBL7721736 | 0.91 | DNM1 (0.48) | CASP2NAAAEPHX1DNM1FAAH | |
| SCHEMBL27347939 | 0.85 | DNM1 (0.64) | CASP2NAAAEPHX1DNM1FAAH | |
| SCHEMBL4894256 | 0.84 | CASP2 (0.55) | CASP2NAAAEPHX1DNM1FAAH | |
| SCHEMBL10769239 | 0.84 | CASP2 (0.55) | CASP2NAAAEPHX1DNM1FAAH | |
| SCHEMBL20841985 | 0.84 | CASP2 (0.55) | CASP2NAAAEPHX1DNM1FAAH | |
| SCHEMBL7850881 | 0.84 | CASP2 (0.55) | CASP2NAAAEPHX1DNM1FAAH | |
| SCHEMBL12747306 | 0.83 | EPHX2 (0.52) | CASP2DNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010010827-A1 | Method and composition for treatment of headache using magnesium | ALTURA BURTON M (US) | 2001-08-02 | — | — | US | disclosed |
| US-6218192-B1 | TREATING HEADACHE IN A PATIENT HAVING BELOW NORMAL SERUM IONIZED MAGNESIUM CONCENTRATION BY ADMINISTERING A WATER SOLUBLE MAGNESIUM SALT SUCH AS MAGNESIUM CHLORIDE AT GIVEN DOSAGE | RESEARCH FOUNDATION OF THE STATE UNIVERSITY OF NEW YORK | 2001-04-17 | — | — | US | disclosed |
| US-6100095-A | MONITORING METAL CONCENTRATION IN BLOOD, CEREBRAL SPINAL FLUID AND AMNIOTIC FLUID; RECOVERING AND MAINTAINING SAMPLE UNDER AEROBIC CONDITIONS, MONITOR METAL CONCENTRATION OF SAMPLES USING A PREFERENTIAL ION ELECTRODE | THE RESEARCH FOUNDATION OF THE STATE UNIVERSITY OF NEW YORK | 2000-08-08 | — | — | US | disclosed |
| US-5460972-A | Using ion selective electrodes; diagnosis, prognosis | RESEARCH FOUNDATION OF THE STATE UNIVERSITY OF NEW YORK (US) | 1995-10-24 | — | — | US | disclosed |
| US-5364642-A | Ionized magnesium2+ concentrations in biological samples | RESEARCH FOUNDATION OF THE STATE UNIVERSITY OF NEW YORK (US) | 1994-11-15 | — | — | US | disclosed |
| EP-0579782-A1 | METHOD FOR ASSAYING IONIZED MAGNESIUM AND CALCIUM CONCENTRATIONS AND A COMPOSITION OF BIOAVAILABLE MAGNESIUM AND CALCIUM | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1994-01-26 | — | — | EP | disclosed |
| WO-1992017780-A1 | METHOD FOR ASSAYING IONIZED MAGNESIUM AND CALCIUM CONCENTRATIONS AND A COMPOSITION OF BIOAVAILABLE MAGNESIUM AND CALCIUM | RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1992-10-15 | — | — | WO | disclosed |