SCHEMBL7918797

SCHEMBL7918797

Brc1cc2c(c(Br)c1Br)O2

nearest known ligand 0.86

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
AHR P35869 10/20 0.86
ALOX15 P16050 2/20 0.42
ALOX12 P18054 2/20 0.42
APEX1 P27695 1/20 0.36
TDP1 Q9NUW8 1/20 0.35
AKR1B1 P15121 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA4 P22748 1/20 0.31
CA6 P23280 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32668978 0.93 AHR (1.00) AHRALOX15ALOX12APEX1TDP1
SCHEMBL5586746 0.85 AHR (0.64) AHRALOX15ALOX12TDP1AKR1B1
SCHEMBL5588910 0.80 AHR (0.58) AHRALOX15ALOX12AKR1B1CA1
SCHEMBL5590075 0.76 AHR (0.53) AHRALOX15ALOX12AKR1B1CA1
SCHEMBL28573522 0.74 AHR (0.52) AHRALOX15ALOX12
SCHEMBL4252719 0.69 AHR (0.47) AHRALOX15ALOX12
SCHEMBL5590303 0.67 ALOX15 (0.46) AHRALOX15ALOX12CA1CA2
SCHEMBL30599776 0.67
SCHEMBL9344843 0.65 AHR (1.00) AHRALOX15ALOX12APEX1
SCHEMBL8712723 0.63 AHR (0.41) AHRALOX15ALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0960910-B1 Flame-retardant aromatic polyamide resin compositions UBE INDUSTRIES (JP) 2001-10-10 EP disclosed
EP-0960910-A1 Flame-retardant aromatic polyamide resin compositions Ube Industries, Ltd. (JP) 1999-12-01 EP disclosed
US-5200454-A Blend of syndiotactic polymer, thermoplastic resin, halogenated polystyrenes and phosphine oxide IDEMITSU KOSAN COMPANY LIMITED (JP) 1993-04-06 US disclosed
US-5047459-A POLYAMIDES, POLYESTERS, AND MIXTURE OF MELAMINE AND ADDUCT OF CAPROLACTAM AND HEXAMETHYLENE DIISOCYANATE; SELF EXTINGUISHING L. Bruggemann Komm.-GES. (DE) 1991-09-10 US disclosed