Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7924081 | 1.00 | ALDH1A1 (0.46) | ALDH1A1HPGDHSD17B10PLA2G4BPTPN1 | |
| SCHEMBL7911884 | 0.88 | MAPT (0.47) | ALDH1A1HPGDPTPN1MAPTTBXA2R | |
| SCHEMBL7918931 | 0.88 | MAPT (0.47) | ALDH1A1HPGDPTPN1MAPTTBXA2R | |
| SCHEMBL11107638 | 0.84 | ALDH1A1 (0.59) | ALDH1A1HPGDHSD17B10PLA2G4BTBXA2R | |
| SCHEMBL8440775 | 0.81 | MEN1 (0.48) | ALDH1A1HPGDPTPN1CNR2 | |
| SCHEMBL8441453 | 0.81 | MEN1 (0.48) | ALDH1A1HPGDPTPN1CNR2 | |
| SCHEMBL7918947 | 0.79 | ALDH1A1 (0.63) | ALDH1A1HPGDHSD17B10MAPTTBXA2R | |
| SCHEMBL7911810 | 0.78 | ALDH1A1 (0.39) | ALDH1A1HPGDPLA2G4BMAPTCNR2 | |
| SCHEMBL7911920 | 0.78 | ALDH1A1 (0.39) | ALDH1A1HPGDPLA2G4BMAPTCNR2 | |
| SCHEMBL7911917 | 0.76 | ALDH1A1 (0.41) | ALDH1A1HSD17B10PLA2G4BCNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0811375-B1 | GLUTAMIC ACID RECEPTOR AGONIST | NIPPON SUISAN KAISHA LTD (JP) | 2001-01-03 | — | — | EP | disclosed |
| EP-0811375-A1 | GLUTAMIC ACID RECEPTOR AGONIST | NIPPON SUISAN KAISHA, LTD. (JP) | 1997-12-10 | — | — | EP | disclosed |
| EP-0469901-B1 | Sulfonamide derivatives | TAISHO PHARMACEUTICAL CO LTD (JP) | 1994-10-19 | — | — | EP | disclosed |
| US-5189211-A | Thromboxane A2 antagonists | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1993-02-23 | — | — | US | disclosed |
| EP-0469901-A1 | Sulfonamide derivatives | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1992-02-05 | — | — | EP | disclosed |