Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | PAM | P19021 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8441453 | 1.00 | MEN1 (0.48) | MEN1KMT2AALDH1A1HPGDPTPN1 | |
| SCHEMBL14602835 | 0.81 | ALDH1A1 (0.63) | ALDH1A1PTPN1 | |
| SCHEMBL7918974 | 0.81 | ALDH1A1 (0.46) | ALDH1A1HPGDPTPN1CNR2 | |
| SCHEMBL7924081 | 0.81 | ALDH1A1 (0.46) | ALDH1A1HPGDPTPN1CNR2 | |
| SCHEMBL8442905 | 0.80 | POLB (0.55) | MEN1KMT2AALDH1A1HPGDPAM | |
| SCHEMBL7918931 | 0.76 | MAPT (0.47) | ALDH1A1HPGDPTPN1CNR2 | |
| SCHEMBL7911884 | 0.76 | MAPT (0.47) | ALDH1A1HPGDPTPN1CNR2 | |
| SCHEMBL8441450 | 0.76 | SOAT2 (0.46) | KMT2AALDH1A1PTPN1 | |
| SCHEMBL8440773 | 0.76 | SOAT2 (0.46) | KMT2AALDH1A1PTPN1 | |
| SCHEMBL11107638 | 0.75 | ALDH1A1 (0.59) | ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5955505-A | TREATING NERVE DEGENERATIVE DISORDERS | NIPPON SUISAN KAISHA, LTD. (JP) | 1999-09-21 | — | — | US | disclosed |