Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.48 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7924098 | 0.90 | ALDH1A1 (0.47) | ALDH1A1CYP2C9CYP2C19GRIN1GRIN2B | |
| SCHEMBL7911845 | 0.89 | GRIN1 (0.47) | ALDH1A1CYP2C9GRIN1GRIN2BHTT | |
| SCHEMBL7924092 | 0.86 | ACLY (0.50) | ALDH1A1CYP2C9CYP2C19GRIN1GRIN2B | |
| SCHEMBL7919288 | 0.80 | ALDH1A1 (0.66) | ALDH1A1CYP2C9CYP2C19HTTTSHR | |
| SCHEMBL7911928 | 0.80 | ALDH1A1 (0.50) | ALDH1A1CYP2C9CYP2C19HTTTSHR | |
| SCHEMBL7918880 | 0.79 | ALDH1A1 (0.52) | ALDH1A1CYP2C9CYP2C19GRIN1GRIN2B | |
| SCHEMBL7918958 | 0.79 | ALDH1A1 (0.65) | ALDH1A1CYP2C9CYP2C19HTTTSHR | |
| SCHEMBL7920576 | 0.79 | ALDH1A1 (0.52) | ALDH1A1CYP2C9CYP2C19HTTTSHR | |
| SCHEMBL7924121 | 0.79 | GRIN1 (0.46) | ALDH1A1GRIN1GRIN2BHTTTSHR | |
| SCHEMBL7911909 | 0.78 | ALDH1A1 (0.63) | ALDH1A1CYP2C9CYP2C19HTTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0811375-B1 | GLUTAMIC ACID RECEPTOR AGONIST | NIPPON SUISAN KAISHA LTD (JP) | 2001-01-03 | — | — | EP | disclosed |
| US-5955505-A | TREATING NERVE DEGENERATIVE DISORDERS | NIPPON SUISAN KAISHA, LTD. (JP) | 1999-09-21 | — | — | US | disclosed |
| EP-0811375-A1 | GLUTAMIC ACID RECEPTOR AGONIST | NIPPON SUISAN KAISHA, LTD. (JP) | 1997-12-10 | — | — | EP | disclosed |
| EP-0469901-B1 | Sulfonamide derivatives | TAISHO PHARMACEUTICAL CO LTD (JP) | 1994-10-19 | — | — | EP | disclosed |
| US-5189211-A | Thromboxane A2 antagonists | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1993-02-23 | — | — | US | disclosed |
| EP-0469901-A1 | Sulfonamide derivatives | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1992-02-05 | — | — | EP | disclosed |