Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 3/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.35 |
| ▸ | DRD3 | P35462 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | HRH2 | P25021 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL320363 | 0.78 | MAPT (0.44) | CHRM2CHRM1LMNACHRM4CHRM5 | |
| SCHEMBL2454589 | 0.73 | PIK3CD (0.42) | CHRM2CHRM1LMNACHRM4CHRM5 | |
| SCHEMBL5892098 | 0.73 | PIK3CD (0.42) | CHRM2CHRM1CHRM4CHRM5CHRM3 | |
| SCHEMBL35893 | 0.73 | — | — | |
| SCHEMBL29315685 | 0.73 | — | — | |
| SCHEMBL3731822 | 0.73 | CHRM2 (0.42) | CHRM2CHRM1LMNACHRM4CHRM5 | |
| SCHEMBL28643566 | 0.73 | MAPT (0.34) | CHRM2CHRM1LMNACHRM4CHRM5 | |
| Dimethylamine SCHEMBL7919126 | 0.72 | THRB (0.33) | LMNA | |
| SCHEMBL10794918 | 0.70 | CHRM2 (0.46) | CHRM2CHRM1LMNACHRM4CHRM5 | |
| SCHEMBL8849598 | 0.70 | CHRM2 (0.39) | CHRM2CHRM1LMNACHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1120192-C | Active methano-compound containing tertiary amine for improving stability of size of polyurethane | AIR PROD & CHEM (US) | 2003-09-03 | — | — | CN | claimed |
| EP-0140480-B1 | THE PREPARATION OF POLYURETHANES USING MONOCARBOXYLIC ACID SALTS OF BIS(AMINOETHYL) ETHER DERIVATIVES AS CATALYSTS | TEXACO DEVELOPMENT CORPORATION (US) | 1987-04-15 | — | — | EP | claimed |
| EP-0140480-A1 | The preparation of polyurethanes using monocarboxylic acid salts of bis(aminoethyl) ether derivatives as catalysts | TEXACO DEVELOPMENT CORPORATION (US) | 1985-05-08 | — | — | EP | claimed |
| US-4433170-A | Novel bis(aminoethyl)ether derivatives useful as polyurethane catalysts | TEXACO INC. (US) | 1984-02-21 | — | — | US | claimed |
| CN-1120192-C | Active methano-compound containing tertiary amine for improving stability of size of polyurethane | AIR PROD & CHEM (US) | 2003-09-03 | — | — | CN | disclosed |
| US-6248801-B1 | CELL OPENING ADJUVANTS | AIR PRODUCTS AND CHEMICALS, INC. | 2001-06-19 | — | — | US | disclosed |