Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.36 |
| ▸ | DRD3 | P35462 | 3/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.36 |
| ▸ | HRH2 | P25021 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.36 |
| ▸ | HRH1 | P35367 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27985703 | 0.88 | MAPT (0.41) | MAPTTSHRKDM4ESMN1; SMN2CHRNB2 | |
| SCHEMBL28643566 | 0.86 | MAPT (0.34) | MAPTCHRM2CHRM1CHRM4CHRM5 | |
| SCHEMBL2454589 | 0.79 | PIK3CD (0.42) | CHRM2CHRM1CHRM4CHRM5CHRM3 | |
| SCHEMBL7919129 | 0.78 | CHRM2 (0.35) | CHRM2CHRM1CHRM4CHRM5CHRM3 | |
| SCHEMBL8061822 | 0.75 | SLC6A2 (0.30) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL3731822 | 0.75 | CHRM2 (0.42) | MAPTCHRM2CHRM1CHRM4CHRM5 | |
| SCHEMBL28341029 | 0.72 | MAPT (0.40) | MAPTCHRM2CHRM1CHRM4CHRM5 | |
| SCHEMBL21386345 | 0.71 | CHRM2 (0.39) | MAPTCHRM2CHRM1CHRM4CHRM5 | |
| SCHEMBL9320446 | 0.71 | CHRNB2 (0.36) | MAPTSLC6A2SLC6A4SLC6A3LMNA | |
| SCHEMBL28989966 | 0.70 | CHRM2 (0.42) | MAPTCHRM2CHRM1CHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 558 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4253442-B1 | AMINE COMPOSITION USEFUL FOR MAKING STABLE POLYURETHANE FOAM SYSTEMS | EVONIK OPERATIONS GMBH (DE) | 2026-04-29 | — | — | EP | claimed |
| EP-3849701-B1 | POLYURETHANE INSULATION FOAM COMPOSITION COMPRISING A STABILIZING COMPOUND | HUNTSMAN INT LLC (US) | 2026-04-22 | — | — | EP | claimed |
| US-12600813-B2 | Polyurethane insulation foam composition comprising a stabilizing compound | HUNTSMAN INTERNATIONAL LLC | 2026-04-14 | — | — | US | claimed |
| EP-4720149-A1 | AMINE CATALYSTS FOR POLYURETHANE APPLICATIONS | Evonik Operations GmbH (DE) | 2026-04-08 | — | — | EP | claimed |
| US-20260028445-A1 | AMINE COMPOSITION USEFUL FOR MAKING STABLE POLYURETHANE FOAM SYSTEMS | EVONIK OPERATIONS GMBH (DE) | 2026-01-29 | — | — | US | claimed |
| EP-4674882-A2 | POLYURETHANE INSULATION FOAM COMPOSITION COMPRISING A STABILIZING COMPOUND | Huntsman International LLC (US) | 2026-01-07 | — | — | EP | claimed |
| EP-3303440-B1 | REACTIVE AMINE CATALYSTS FOR POLYURETHANE APPLICATIONS | EVONIK OPERATIONS GMBH (DE) | 2025-08-06 | — | — | EP | claimed |
| EP-4562070-A1 | METHOD FOR PREPARING FLEXIBLE SLABSTOCK POLYURETHANE FOAM | Evonik Operations GmbH (DE) | 2025-06-04 | — | — | EP | claimed |
| EP-4562069-A1 | TERTIARY AMINO-AMIDE COMPOSITION USEFUL IN MAKING POLYURETHANE POLYMERS | Evonik Operations GmbH (DE) | 2025-06-04 | — | — | EP | claimed |
| WO-2025040451-A1 | HYDROLYSIS RESISTANCE OF POLYURETHANE FOAMS | EVONIK OPERATIONS GMBH (DE) | 2025-02-27 | — | — | WO | claimed |
| EP-1435365-A2 | Tertiary amino alkyl amide catalysts for improving the physical properties of polyurethane foams | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2004-07-07 | — | — | EP | claimed |
| US-6747069-B1 | PREPARING A POLYURETHANE FOAM WHICH COMPRISES REACTING AN ORGANIC POLYISOCYANATE AND A POLYOL IN THE PRESENCE OF WATER AS A BLOWING AGENT, A CELL STABILIZER, AND A TERTIARY AMINE AMIDE CATALYST COMPOSITION | AIR PRODUCTS AND CHEMICALS, INC. | 2004-06-08 | — | — | US | claimed |
| US-6737446-B1 | POROSITY, OPENNESS; DIMENSIONAL STABILITY | AIR PRODUCTS AND CHEMICALS, INC. | 2004-05-18 | — | — | US | claimed |
| CN-1120192-C | Active methano-compound containing tertiary amine for improving stability of size of polyurethane | AIR PROD & CHEM (US) | 2003-09-03 | — | — | CN | claimed |
| CN-1300792-A | Active methano-compound containing tertiary amine for improving stability of size of polyurethane | AIR PROD & CHEM (US) | 2001-06-27 | — | — | CN | claimed |
| EP-1099718-A2 | Tertiary amine-containing active methylene compounds for improving the dimensional stability of polyurethane foam | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2001-05-16 | — | — | EP | claimed |
| EP-0140480-B1 | THE PREPARATION OF POLYURETHANES USING MONOCARBOXYLIC ACID SALTS OF BIS(AMINOETHYL) ETHER DERIVATIVES AS CATALYSTS | TEXACO DEVELOPMENT CORPORATION (US) | 1987-04-15 | — | — | EP | claimed |
| EP-0140480-A1 | The preparation of polyurethanes using monocarboxylic acid salts of bis(aminoethyl) ether derivatives as catalysts | TEXACO DEVELOPMENT CORPORATION (US) | 1985-05-08 | — | — | EP | claimed |
| US-4433170-A | Novel bis(aminoethyl)ether derivatives useful as polyurethane catalysts | TEXACO INC. (US) | 1984-02-21 | — | — | US | claimed |
| US-4338408-A | Polyurethanes using bis(aminoethyl)ether derivatives as catalysts | TEXACO INC. (US) | 1982-07-06 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260028445-A1 | AMINE COMPOSITION USEFUL FOR MAKING STABLE POLYURETHANE FOAM SYSTEMS | RFC2, RFC3, PUF60 | MAPT 2326/4885CHRM2 149/4885CHRM1 70/4885 |
| US-12600813-B2 | Polyurethane insulation foam composition comprising a stabilizing compound | TAF1, F7, TAF9 | MAPT 1547/4885CHRM2 1061/4885CHRM1 1045/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.