Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diclazuril SCHEMBL27803573 | 0.88 | MEN1 (0.64) | MEN1KMT2ANR1I2L3MBTL1ALDH1A1 | |
| Diclazuril SCHEMBL126138 | 0.80 | MEN1 (1.00) | MEN1KMT2ANR1I2L3MBTL1 | |
| SCHEMBL10395312 | 0.79 | MEN1 (0.67) | MEN1KMT2ANR1I2L3MBTL1ALDH1A1 | |
| SCHEMBL7919164 | 0.77 | MEN1 (0.65) | MEN1KMT2ANR1I2L3MBTL1ALDH1A1 | |
| SCHEMBL7917605 | 0.74 | SMN1; SMN2 (0.53) | KMT2AALDH1A1LMNASMN1; SMN2HTT | |
| SCHEMBL10394514 | 0.74 | MEN1 (0.58) | MEN1KMT2ANR1I2L3MBTL1ALDH1A1 | |
| SCHEMBL7919703 | 0.73 | MEN1 (0.86) | MEN1KMT2ANR1I2L3MBTL1 | |
| SCHEMBL7910062 | 0.73 | NPBWR1 (0.40) | ALDH1A1LMNASMN1; SMN2HTTMAPT | |
| SCHEMBL7917028 | 0.72 | MEN1 (0.69) | MEN1KMT2ANR1I2L3MBTL1ALDH1A1 | |
| Letrazuril SCHEMBL466345 | 0.71 | MEN1 (0.83) | MEN1KMT2ANR1I2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211178-B1 | ANTIPROTOZOA AGENTS FOR COCCIDIOIDES; CYCLIZATION | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-04-03 | — | — | US | disclosed |
| US-5994355-A | ANTIPROTOZOA AGENTS, PARASITICIDE; VETERINARY MEDICINE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-11-30 | — | — | US | disclosed |
| EP-0648760-B1 | Triazine derivative, production and use thereof | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1999-01-27 | — | — | EP | disclosed |
| EP-0648760-A2 | Triazine derivative, production and use thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-04-19 | — | — | EP | disclosed |