Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | CDK4 | P11802 | 1/20 | 0.34 |
| ▸ | CCND1 | P24385 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7917605 | 0.83 | SMN1; SMN2 (0.53) | NPBWR1MCHR1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7910204 | 0.79 | NPBWR1 (0.49) | NPBWR1MCHR1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7919778 | 0.76 | NPSR1 (0.48) | NPC1RAB9ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL7919792 | 0.68 | MEN1 (0.56) | THRB | |
| SCHEMBL11284453 | 0.68 | ATM (0.40) | NPBWR1MCHR1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1750028 | 0.68 | NPBWR1 (0.39) | NPBWR1MCHR1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4062470 | 0.68 | NPBWR1 (0.42) | NPBWR1MCHR1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1751460 | 0.67 | RAB9A (0.62) | NPBWR1MCHR1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10395039 | 0.66 | NOTUM (0.42) | NPC1RAB9ASMN1; SMN2MAPK1ALDH1A1 | |
| SCHEMBL7922440 | 0.66 | KMT2A (0.41) | NPBWR1MCHR1LMNAALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211178-B1 | ANTIPROTOZOA AGENTS FOR COCCIDIOIDES; CYCLIZATION | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-04-03 | — | — | US | disclosed |
| US-5994355-A | ANTIPROTOZOA AGENTS, PARASITICIDE; VETERINARY MEDICINE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-11-30 | — | — | US | disclosed |
| EP-0648760-B1 | Triazine derivative, production and use thereof | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1999-01-27 | — | — | EP | disclosed |
| EP-0648760-A2 | Triazine derivative, production and use thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-04-19 | — | — | EP | disclosed |