Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7917746 | 0.92 | SCN8A (0.32) | SCN8AKDM4ELMNAMAPTHTT | |
| SCHEMBL7917715 | 0.92 | SCN8A (0.34) | SCN8AKDM4ELMNAMAPTHTT | |
| SCHEMBL7919222 | 0.86 | CNR1 (0.33) | SCN8AKDM4ELMNAMAPTHTT | |
| SCHEMBL7916983 | 0.80 | CYP3A4 (0.34) | SCN8AKDM4ELMNAMAPTHTT | |
| SCHEMBL7922600 | 0.80 | MEN1 (0.32) | — | |
| SCHEMBL7917047 | 0.76 | CYP3A4 (0.31) | — | |
| SCHEMBL7917708 | 0.73 | CHEK2 (0.35) | — | |
| SCHEMBL7919224 | 0.72 | MEN1 (0.33) | KDM4ELMNAMAPTSMN1; SMN2 | |
| SCHEMBL7917733 | 0.72 | MEN1 (0.33) | SCN8ALMNA | |
| SCHEMBL7917015 | 0.71 | DRD4 (0.32) | LMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211178-B1 | ANTIPROTOZOA AGENTS FOR COCCIDIOIDES; CYCLIZATION | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-04-03 | — | — | US | disclosed |
| US-5994355-A | ANTIPROTOZOA AGENTS, PARASITICIDE; VETERINARY MEDICINE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-11-30 | — | — | US | disclosed |
| EP-0648760-B1 | Triazine derivative, production and use thereof | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1999-01-27 | — | — | EP | disclosed |
| EP-0648760-A2 | Triazine derivative, production and use thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-04-19 | — | — | EP | disclosed |