Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK2 | O96017 | 1/20 | 0.35 |
| ▸ | TOP2A | P11388 | 1/20 | 0.33 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.30 |
| ▸ | DRD4 | P21917 | 3/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7919693 | 0.87 | MEN1 (0.34) | CYP3A4ROCK2DRD4MEN1NR1I2 | |
| SCHEMBL7917047 | 0.86 | CYP3A4 (0.31) | CYP3A4CYP2D6MEN1NR1I2KMT2A | |
| SCHEMBL7990341 | 0.80 | ALDH1A1 (0.33) | DRD4 | |
| SCHEMBL7917049 | 0.77 | MEN1 (0.34) | MEN1NR1I2KMT2A | |
| SCHEMBL7917510 | 0.77 | MEN1 (0.34) | MEN1NR1I2KMT2A | |
| SCHEMBL7917015 | 0.77 | DRD4 (0.32) | CYP2D6DRD4MEN1NR1I2KMT2A | |
| SCHEMBL7917715 | 0.76 | SCN8A (0.34) | CYP3A4 | |
| SCHEMBL7910016 | 0.75 | SRD5A2 (0.43) | CHEK2MEN1KMT2A | |
| SCHEMBL7917733 | 0.75 | MEN1 (0.33) | MEN1NR1I2KMT2A | |
| SCHEMBL7919224 | 0.75 | MEN1 (0.33) | CYP2D6DRD4MEN1NR1I2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211178-B1 | ANTIPROTOZOA AGENTS FOR COCCIDIOIDES; CYCLIZATION | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-04-03 | — | — | US | disclosed |
| US-5994355-A | ANTIPROTOZOA AGENTS, PARASITICIDE; VETERINARY MEDICINE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-11-30 | — | — | US | disclosed |
| EP-0648760-B1 | Triazine derivative, production and use thereof | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1999-01-27 | — | — | EP | disclosed |
| EP-0648760-A2 | Triazine derivative, production and use thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-04-19 | — | — | EP | disclosed |