Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | TLR4 | O00206 | 1/20 | 0.31 |
| ▸ | TLR2 | O60603 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7913020 | 0.88 | F2 (0.38) | MEN1KMT2A | |
| SCHEMBL7913124 | 0.75 | CES2 (0.35) | MEN1KMT2A | |
| SCHEMBL7921835 | 0.74 | — | — | |
| SCHEMBL4431394 | 0.69 | — | — | |
| SCHEMBL16005111 | 0.67 | — | — | |
| SCHEMBL27502523 | 0.65 | CES2 (0.38) | SMN1; SMN2MEN1KMT2A | |
| SCHEMBL9788468 | 0.64 | MEN1 (0.33) | ALOX5MEN1KMT2A | |
| SCHEMBL16005069 | 0.62 | BCL9 (0.36) | — | |
| SCHEMBL10426165 | 0.61 | — | — | |
| SCHEMBL3618771 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6291442-B1 | Pharmacological modulators of voltage-gated potassium ion channels | THE GENERAL HOSPITAL CORPORATION | 2001-09-18 | — | — | US | disclosed |