Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7919728 | 0.88 | ALOX5 (0.33) | MEN1KMT2A | |
| SCHEMBL7921835 | 0.69 | — | — | |
| SCHEMBL7913124 | 0.68 | CES2 (0.35) | F2TP53ALDH1A1TSHRCES2 | |
| SCHEMBL29709134 | 0.66 | MEN1 (0.63) | F2TP53ALDH1A1HGFACTSHR | |
| SCHEMBL148916 | 0.66 | MEN1 (0.63) | F2TP53ALDH1A1HGFACTSHR | |
| SCHEMBL11195246 | 0.65 | F2 (0.61) | F2TP53ALDH1A1HGFACTSHR | |
| SCHEMBL7929197 | 0.63 | F2 (0.63) | F2TP53ALDH1A1HGFACTSHR | |
| SCHEMBL2955782 | 0.63 | F2 (0.63) | F2TP53ALDH1A1HGFACTSHR | |
| SCHEMBL4766454 | 0.63 | TSHR (0.61) | F2ALDH1A1HGFACTSHRCES2 | |
| SCHEMBL4203388 | 0.62 | TSHR (0.67) | F2ALDH1A1TSHRLPAR3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6291442-B1 | Pharmacological modulators of voltage-gated potassium ion channels | THE GENERAL HOSPITAL CORPORATION | 2001-09-18 | — | — | US | claimed |
| US-6291442-B1 | Pharmacological modulators of voltage-gated potassium ion channels | THE GENERAL HOSPITAL CORPORATION | 2001-09-18 | — | — | US | disclosed |