Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | FDPS | P14324 | 3/20 | 0.33 |
| ▸ | SMPD1 | P17405 | 4/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | THPO | P40225 | 1/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | GGPS1 | O95749 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22010421 | 0.78 | MEN1 (0.50) | MEN1KMT2AFDPSSMPD1GGPS1 | |
| SCHEMBL24401029 | 0.78 | MEN1 (0.50) | MEN1KMT2AFDPSSMPD1GGPS1 | |
| SCHEMBL22951430 | 0.69 | FDPS (0.33) | FDPSSMPD1GGPS1 | |
| SCHEMBL22955304 | 0.68 | EPHX1 (0.31) | FDPSGGPS1 | |
| Iodide SCHEMBL11685953 | 0.67 | NOS1 (0.50) | MEN1KMT2ACYP2C19THPONOS3 | |
| SCHEMBL22666450 | 0.67 | GGPS1 (0.35) | MEN1KMT2AFDPSSMPD1GGPS1 | |
| SCHEMBL25766806 | 0.67 | GGPS1 (0.35) | MEN1KMT2AFDPSSMPD1GGPS1 | |
| SCHEMBL22021840 | 0.67 | GGPS1 (0.35) | MEN1KMT2AFDPSSMPD1GGPS1 | |
| SCHEMBL23505664 | 0.67 | — | — | |
| SCHEMBL18793246 | 0.63 | GGPS1 (0.38) | FDPSSMPD1GGPS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010098488-A1 | ARYL IMIDAZOLE COMPOUNDS AND THEIR USE AS BETA AMYLOID PRODUCTION INHIBITORS | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2010-09-02 | — | — | WO | disclosed |