SCHEMBL119384

SCHEMBL119384

O=C(NCc1ccccc1C(=O)O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.56

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.56
EPHX2 P34913 1/20 0.48
FABP7 O15540 2/20 0.44
FABP5 Q01469 2/20 0.44
CASP3 P42574 2/20 0.43
MDM4 O15151 1/20 0.41
TP53 P04637 1/20 0.41
OPRD1 P41143 1/20 0.41
KCNA5 P22460 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30421786 1.00 KMT2A (0.56) KMT2AEPHX2FABP7FABP5CASP3
SCHEMBL27645062 0.85 KMT2A (0.52) KMT2AEPHX2FABP7FABP5CASP3
SCHEMBL26140029 0.85 KMT2A (0.59) KMT2AEPHX2FABP7FABP5CASP3
SCHEMBL18687752 0.84 KMT2A (0.55) KMT2AEPHX2FABP7FABP5CASP3
SCHEMBL525568 0.84 KMT2A (0.58) KMT2AEPHX2FABP7FABP5CASP3
SCHEMBL29097418 0.83 KMT2A (0.59) KMT2AEPHX2FABP7FABP5CASP3
SCHEMBL2744610 0.83 KMT2A (0.54) KMT2AEPHX2FABP7FABP5CASP3
SCHEMBL7920181 0.83 KMT2A (0.52) KMT2AEPHX2FABP7FABP5CASP3
SCHEMBL28330792 0.83 KMT2A (0.49) KMT2AEPHX2FABP7FABP5CASP3
SCHEMBL3177417 0.82 KMT2A (0.62) KMT2AEPHX2FABP7FABP5CASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116535459-A Phenolic acid compound and synthesis method and application thereof 西北大学 2023-08-04 CN claimed
US-20250108138-A1 THERAGNOSTIC FOLATE CONJUGATES MERCK PATENT GMBH (DE) 2025-04-03 US disclosed
EP-4472676-A1 THERAGNOSTIC FOLATE CONJUGATES Merck Patent GmbH (DE) 2024-12-11 EP disclosed
CN-118660723-A Therapeutic diagnostic folate conjugates 默克专利股份有限公司 2024-09-17 CN disclosed
WO-2023148115-A1 THERAGNOSTIC FOLATE CONJUGATES MERCK PATENT GMBH (DE) 2023-08-10 WO disclosed
CN-116535459-A Phenolic acid compound and synthesis method and application thereof 西北大学 2023-08-04 CN disclosed
CN-113646329-A Glucose-sensitive insulin derivatives 诺和诺德股份有限公司 2021-11-12 CN disclosed
US-8895231-B2 Patterning process and resist composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-11-25 US disclosed
US-8895231-B2 Patterning process and resist composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-11-25 US disclosed
US-20130136691-A1 GASTRIN RELEASING PEPTIDE COMPOUNDS BRACCO IMAGING S.P.A. (IT) 2013-05-30 US disclosed
US-7611692-B2 bombesin, derivatives and/or analogues capable of complexing metal ions, radionuclides or optical labels, for use in radiotherapy BRACCO IMAGING S.P.A. (IT) 2009-11-03 US disclosed
US-20090175786-A1 Gastrin Releasing Peptide Compounds BRACCO IMAGING S.P.A. (IT) 2009-07-09 US disclosed
US-20080247946-A1 Bombesin capable of complexing with metal ions, radionuclides, or optical labels; radiotherapy BRACCO IMAGING S.P.A. (IT) 2008-10-09 US disclosed
US-20080008649-A1 Gastrin Releasing Peptide Compounds BRACCO IMAGING S.P.A. (IT) 2008-01-10 US disclosed
WO-2007117404-A9 METHODS AND MATERIALS FOR PREPARING ORGANIC COMPOUNDS FROM PRIMARY AMINES UNIV VIRGINIA (US) 2007-11-29 WO disclosed
WO-2007117404-A2 METHODS AND MATERIALS FOR PREPARING ORGANIC COMPOUNDS FROM PRIMARY AMINES UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) 2007-10-18 WO disclosed
US-7226577-B2 Gastrin releasing peptide compounds BRACCO IMAGING, S. P. A. (IT) 2007-06-05 US disclosed
US-20050019831-A1 Facilitated forward chemical genetics using tagged triazine library NEW YORK UNIVERSITY (US) 2005-01-27 US disclosed
WO-2004099106-A2 FACILITATED FORWARD CHEMICAL GENETICS USING TAGGED TRIAZINE LIBRARY NEW YORK UNIVERSITY (US) 2004-11-18 WO disclosed
US-6034056-A CYCLIC PEPTIDES; ANTIARTHRITIC AGENTS ZENECA LIMITED (GB) 2000-03-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250108138-A1 THERAGNOSTIC FOLATE CONJUGATES FOLR1, MTHFD1, MTHFD2 KMT2A 1726/4885EPHX2 992/4885FABP7 43/4885
US-20130136691-A1 GASTRIN RELEASING PEPTIDE COMPOUNDS GRPR, GIPR, GHRHR KMT2A 4582/4885EPHX2 4140/4885FABP7 336/4885
US-20090175786-A1 Gastrin Releasing Peptide Compounds GRPR, SSTR5, GIPR KMT2A 2078/4885EPHX2 3872/4885FABP7 300/4885
US-20080008649-A1 Gastrin Releasing Peptide Compounds GRPR, SSTR5, GIPR KMT2A 2078/4885EPHX2 3872/4885FABP7 300/4885
US-20080247946-A1 Bombesin capable of complexing with metal ions, radionuclides, or optical labels; radiotherapy GRPR, MRGPRX1, BRS3 KMT2A 4425/4885EPHX2 3747/4885FABP7 627/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.