SCHEMBL7920405

SCHEMBL7920405

Cn1ncc(C2CN3CCC2CC3)n1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CHRNA7 P36544 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10433628 0.92
Oxalic Acid SCHEMBL9585176 0.84
SCHEMBL10433632 0.72
SCHEMBL9458933 0.71 CHRNA7 (0.43) CHRNA7
SCHEMBL10433659 0.70 CHRNA7 (0.42) CHRNA7
SCHEMBL9458898 0.69
SCHEMBL9710719 0.69
SCHEMBL9459439 0.68 CHRM2 (0.48) CHRNA7
SCHEMBL7820147 0.68 CHRNA7 (0.43) CHRNA7
SCHEMBL10433635 0.68 CHRNA7 (0.40) CHRNA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0402056-A2 Azabicyclic compounds, process for their preparation and pharmaceutical compositions containing them Beecham Group p.l.c. (GB) 1990-12-12 EP claimed
EP-0871445-A4 COMPOSITION FOR TREATING PAIN LILLY CO ELI (US) 2001-01-10 EP disclosed
EP-0783304-A4 METHOD FOR TREATING ANXIETY LILLY CO ELI (US) 1999-01-27 EP disclosed
US-5852036-A Method for treating anxiety ELI LILLY AND COMPANY (US) 1998-12-22 US disclosed
EP-0871445-A1 COMPOSITION FOR TREATING PAIN ELI LILLY AND COMPANY (US) 1998-10-21 EP disclosed
EP-0783304-A1 METHOD FOR TREATING ANXIETY ELI LILLY AND COMPANY (US) 1997-07-16 EP disclosed
WO-1997020561-A1 COMPOSITION FOR TREATING PAIN ELI LILLY AND COMPANY (US) 1997-06-12 WO disclosed
US-5574053-A Method for treating anxiety ELI LILLY AND COMPANY (US) 1996-11-12 US disclosed
US-5574029-A Method for treating anxiety ELI LILLY AND COMPANY (US) 1996-11-12 US disclosed
US-5574028-A SEDATIVES ELI LILLY AND COMPANY (US) 1996-11-12 US disclosed
WO-1996013261-A1 METHOD FOR TREATING ANXIETY ELI LILLY AND COMPANY (US) 1996-05-09 WO disclosed