SCHEMBL7820147

SCHEMBL7820147

c1nsnc1C1CN2CCC1CC2

nearest known ligand 0.53

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CHRNA7 P36544 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fumaric Acid SCHEMBL7811656 0.87 CHRNA7 (0.38) CHRNA7
Fumaric Acid SCHEMBL7811645 0.87 CHRNA7 (0.38) CHRNA7
SCHEMBL4963428 0.70 CHRNA7 (0.44) CHRNA7
SCHEMBL5931842 0.69 CHRM2 (0.44) CHRNA7
SCHEMBL9585987 0.69 CHRNA7 (0.43) CHRNA7
SCHEMBL9459439 0.69 CHRM2 (0.48) CHRNA7
SCHEMBL9458933 0.69 CHRNA7 (0.43) CHRNA7
SCHEMBL9342833 0.69 CHRNA7 (0.43) CHRNA7
SCHEMBL9148604 0.68 CHRNA7 (0.40) CHRNA7
SCHEMBL7920405 0.68 CHRNA7 (0.42) CHRNA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6281233-B1 AZABICYCLIC RING-SUBSTITUTED THIA- OR OXADIAZOLES NOVO NORDISK A/S (DK) 2001-08-28 US claimed
EP-0714394-B1 ANTIPSYCHOTIC METHOD WITH THIADIAZOLE AND OXADIAZOLE DERIVATIVES NOVO NORDISK AS (DK) 2001-06-20 EP claimed
EP-0735869-A1 A METHOD OF TREATING GASTROINTESTINAL MOTILITY DISORDERS NOVO NORDISK A/S (DK) 1996-10-09 EP claimed
WO-1996014316-A1 A METHOD OF TREATING URINARY BLADDER DYSFUNCTIONS NOVO NORDISK A/S (DK) 1996-05-17 WO claimed
EP-0687266-A1 HETEROCYCLIC COMPOUNDS AND THEIR PREPARATION AND USE NOVO NORDISK A/S (DK) 1995-12-20 EP claimed
WO-1995017180-A1 A METHOD OF TREATING GASTROINTESTINAL MOTILITY DISORDERS NOVO NORDISK A/S (DK) 1995-06-29 WO claimed
WO-1994020496-A1 HETEROCYCLIC COMPOUNDS AND THEIR PREPARATION AND USE NOVO NORDISK A/S (DK) 1994-09-15 WO claimed
CN-1292796-A METH1 and METH2 polynucleotides and polypeptides BETH ISRAEL DICKNY MEDICAL CT (US) 2001-04-25 CN disclosed
EP-0709093-B1 Method for treating anxiety using an azabicyclic oxadiazole or thiadiazole compound LILLY CO ELI (US) 2000-04-05 EP disclosed
WO-1996013166-A1 METHOD FOR TREATING ANXIETY ELI LILLY AND COMPANY (US) 1996-05-09 WO disclosed
EP-0709093-A2 Method for treating anxiety using an azabicyclic oxadiazole or thiadiazole compound ELI LILLY AND COMPANY (US) 1996-05-01 EP disclosed
US-5484794-A THIA- OR OXA-DIAZOLE COMPOUNDS ELI LILLY AND COMPANY (US) 1996-01-16 US disclosed