SCHEMBL7920409

SCHEMBL7920409

CC[SiH](C1C(C)=Cc2c(-c3ccc4ccccc4c3)cccc21)C1C(C)=Cc2c(-c3ccc4ccccc4c3)cccc21

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSTP1 P09211 1/20 0.36
HDAC4 P56524 1/20 0.34
HDAC2 Q92769 1/20 0.34
HDAC8 Q9BY41 1/20 0.34
SLC6A2 P23975 1/20 0.34
SLC6A4 P31645 1/20 0.34
SLC6A3 Q01959 1/20 0.34
DHFR P00374 1/20 0.33
MET P08581 1/20 0.32
HSD17B1 P14061 1/20 0.31
HSD17B2 P37059 1/20 0.31
CNR2 P34972 1/20 0.31
AKR1C3 P42330 1/20 0.31
AKR1C2 P52895 1/20 0.31
AKT1 P31749 1/20 0.31
ADORA2A P29274 1/20 0.31
ADORA1 P30542 1/20 0.31
S1PR5 Q9H228 2/20 0.31
CCNC P24863 1/20 0.31
CDK8 P49336 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL27550862 0.84 GSTP1 (0.36) GSTP1HDAC4HDAC2HDAC8SLC6A2
SCHEMBL27512111 0.81 GSTP1 (0.35) GSTP1HDAC4HDAC2HDAC8SLC6A2
SCHEMBL7940308 0.78 GSTP1 (0.44) GSTP1HDAC4HDAC2HDAC8SLC6A2
SCHEMBL7188594 0.77 GSTP1 (0.35) GSTP1HDAC4HDAC2HDAC8SLC6A2
SCHEMBL8071769 0.77 GSTP1 (0.35) GSTP1HDAC4HDAC2HDAC8SLC6A2
Hydrochloric Acid SCHEMBL7601708 0.76 GSTP1 (0.39) GSTP1HDAC4HDAC2HDAC8SLC6A2
SCHEMBL6234917 0.76 GSTP1 (0.36) GSTP1HDAC4HDAC2HDAC8SLC6A2
SCHEMBL28941567 0.75 GSTP1 (0.38) GSTP1HDAC4HDAC2HDAC8SLC6A2
SCHEMBL3159292 0.75 GSTP1 (0.38) GSTP1HDAC4HDAC2HDAC8SLC6A2
Hydrochloric Acid SCHEMBL29612316 0.75 GSTP1 (0.38) GSTP1HDAC4HDAC2HDAC8SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1109839-A1 HIGHLY ACTIVE SUPPORTED CATALYST COMPOSITIONS ExxonMobil Chemical Patents Inc. (US) 2001-06-27 EP claimed
WO-2000012565-A1 HIGHLY ACTIVE SUPPORTED CATALYST COMPOSITIONS EXXON CHEMICAL PATENTS INC. (US) 2000-03-09 WO claimed