Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTP1 | P09211 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5170143 | 0.97 | GSTP1 (0.36) | GSTP1CYP1A2SMN1; SMN2ALDH1A1CYP3A4 | |
| SCHEMBL5837744 | 0.84 | GSTP1 (0.36) | GSTP1CYP1A2SMN1; SMN2ALDH1A1CYP3A4 | |
| SCHEMBL29366427 | 0.83 | PDCD1 (0.34) | SMN1; SMN2ALDH1A1HPGDTSHRADORA2A | |
| SCHEMBL61908 | 0.83 | PDCD1 (0.34) | SMN1; SMN2ALDH1A1HPGDTSHRADORA2A | |
| SCHEMBL27473458 | 0.83 | GSTP1 (0.41) | GSTP1CYP1A2SMN1; SMN2ALDH1A1CYP3A4 | |
| SCHEMBL7564431 | 0.82 | BRD4 (0.42) | CYP1A2ALDH1A1 | |
| SCHEMBL6648868 | 0.82 | CHEK1 (0.40) | SMN1; SMN2ALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL1454590 | 0.81 | ADORA3 (0.33) | SMN1; SMN2ALDH1A1HPGDKDM4E | |
| SCHEMBL5838399 | 0.81 | PDK2 (0.31) | — | |
| SCHEMBL7940308 | 0.81 | GSTP1 (0.44) | GSTP1CYP1A2SMN1; SMN2ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1270614-B1 | Copolymers containing propylene and alpha-olefin comonomer | BASELL POLYOLEFINE GMBH (DE) | 2010-01-27 | — | — | EP | disclosed |
| US-6984743-B1 | Method for producing metallocenes | BASELL POLYOLEFINE GMBH (DE) | 2006-01-10 | — | — | US | disclosed |
| US-6787618-B1 | TRANSPARENT, STIFF MOLDING MATERIALS; IMPACT TOUGHNESS; FOOD PACKAGING | BASELL POLYPROPYLEN GMBH (DE) | 2004-09-07 | — | — | US | disclosed |
| EP-0776913-B1 | High molecular weight copolymers | BASELL POLYOLEFINE GMBH (DE) | 2004-02-04 | — | — | EP | disclosed |
| US-6620953-B1 | Complexing dimethylbis(2-methyl-4,5-benzoindenyl)silane with transition metal compounds such as 2,4-di-tert-butylphenoxide, zirconium monochloride, to form polymerization catalysts | BASSELL POLYOLEFINE GMBH (DE) | 2003-09-16 | — | — | US | disclosed |
| EP-1133504-B1 | METHOD FOR PRODUCING MONOARYLOXY-ANSA-METALLOCENES | BASELL POLYOLEFINE GMBH (DE) | 2003-03-12 | — | — | EP | disclosed |
| EP-1270614-A2 | Copolymers containing propylene and alpha-olefin comonomer | Basell Polyolefine GmbH (DE) | 2003-01-02 | — | — | EP | disclosed |
| EP-1015463-B1 | METHOD FOR PRODUCING METALLOCENES | BASELL POLYOLEFINE GMBH (DE) | 2002-12-11 | — | — | EP | disclosed |
| EP-0790076-B1 | Catalysts containing metallocenes with arylsubstituted indenyl derivatives as ligands, process and intermediates for the preparation of these metallocenes and their use | BASELL POLYOLEFINE GMBH (DE) | 2001-12-05 | — | — | EP | disclosed |
| US-20010021755-A1 | Metallocenes containing aryl-substituted indenyl derivatives as ligands, process for their preparation, and their use as catalysts | KUBER FRANK (DE) | 2001-09-13 | — | — | US | disclosed |
| US-6242544-B1 | POLYOLEFINS PREPARED USING SOLUBLE METALLOCENE COMPOUNDS IN COMBINATION WITH ALUMINOXANES; HIGH MOLECULAR WEIGHT AND ISOTACTICITY | TARGOR GMBH (DE) | 2001-06-05 | — | — | US | disclosed |
| US-6057408-A | CATALYTIC ADDITION COPOLYMERIZATION OF PROPYLENE WITH ETHYLENE OR OLEFIN | TARGOR GMBH (DE) | 2000-05-02 | — | — | US | disclosed |
| US-6051727-A | A POLYMERIZATION CATALYST FOR POLYOLEFINS OF HIGH MOLECULAR WEIGHT, OF PARTICULAR IMPORTANCE FOR THE PRODUCTION OF FILMS, SHEETS OR LARGE HOLLOW ARTICLES OR MOLDINGS SUCH AS PIPES | TARGOR GMBH (DE) | 2000-04-18 | — | — | US | disclosed |
| US-5840644-A | OLEFIN POLYMERIZATION CATALYSTS | TARGOR GMBH (DE) | 1998-11-24 | — | — | US | disclosed |
| US-5786432-A | POLYMERIZING OR COPOLYMERIZING OLEFIN IN PRESENCE OF TRANSITION METAL METALLOCENE CATALYST AND COCATALYST | TARGOR GMBH (DE) | 1998-07-28 | — | — | US | disclosed |
| US-5770753-A | ADDITION POLYMERIZATION CATALYST | TARGOR GMBH (DE) | 1998-06-23 | — | — | US | disclosed |
| EP-0576970-B1 | Metallocenes with arylsubstituted indenyl-derivatives as ligands, process for their preparation and their use as catalysts | HOECHST AG (DE) | 1998-01-14 | — | — | EP | disclosed |
| EP-0790076-A2 | Catalysts containing metallocenes with arylsubstituted indenyl derivatives as ligands, process and intermediates for the preparation of these metallocenes and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-08-20 | — | — | EP | disclosed |
| EP-0776913-A2 | High molecular weight copolymers | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-06-04 | — | — | EP | disclosed |
| EP-0576970-A1 | Metallocenes with arylsubstituted indenyl-derivatives as ligands, process for their preparation and their use as catalysts | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-01-05 | — | — | EP | disclosed |