Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.61 |
| ▸ | MGAM | O43451 | 4/20 | 0.61 |
| ▸ | SI | P14410 | 3/20 | 0.61 |
| ▸ | MGAM2 | Q2M2H8 | 3/20 | 0.61 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.56 |
| ▸ | PIM1 | P11309 | 4/20 | 0.55 |
| ▸ | PLK1 | P53350 | 4/20 | 0.55 |
| ▸ | NUAK1 | O60285 | 3/20 | 0.55 |
| ▸ | IGF1R | P08069 | 3/20 | 0.55 |
| ▸ | SRC | P12931 | 3/20 | 0.55 |
| ▸ | KDR | P35968 | 3/20 | 0.55 |
| ▸ | PKN1 | Q16512 | 3/20 | 0.55 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.55 |
| ▸ | ALK | Q9UM73 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 6/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.55 |
| ▸ | FTO | Q9C0B1 | 6/20 | 0.55 |
| ▸ | MAOA | P21397 | 6/20 | 0.55 |
| ▸ | APP | P05067 | 5/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12663090 | 0.85 | GAA (0.62) | GAAMGAMSIMGAM2PIM1 | |
| SCHEMBL1858144 | 0.78 | MGAM (0.67) | GAAMGAMSIMGAM2PIM1 | |
| SCHEMBL22738241 | 0.78 | MEN1 (0.78) | GAAMGAMSIMGAM2PIM1 | |
| SCHEMBL9838561 | 0.77 | MGAM (1.00) | GAAMGAMSIMGAM2PGAM1 | |
| SCHEMBL30542658 | 0.77 | MGAM (1.00) | GAAMGAMSIMGAM2PGAM1 | |
| SCHEMBL28315041 | 0.76 | MAOA (0.65) | MGAMMEN1KMT2AFTOMAOA | |
| SCHEMBL12158377 | 0.75 | ABCB1 (0.62) | GAAMGAMSIMGAM2PIM1 | |
| SCHEMBL3778775 | 0.73 | ALDH1A1 (0.75) | GAAMGAMSIMGAM2PGAM1 | |
| SCHEMBL9615139 | 0.73 | NUAK1 (0.58) | GAAMGAMSIMGAM2PGAM1 | |
| SCHEMBL1855594 | 0.73 | KDM4E (0.60) | GAAMGAMSIMGAM2PIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010033847-A1 | NGAL-BINDING SIDEROPHORES AND USE THEREOF TO TREAT IRON DEFICIENCY AND IRON OVERLOAD | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2010-03-25 | — | — | WO | disclosed |